Cross delay line detectors for high time resolution astronomical polarimetry and biological fluorescence imaging
Cross delay line detectors for high time resolution astronomical polarimetry and biological fluorescence imaging
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DOI：
10.1109/nssmic.2005.1596290
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发表时间：
2005
期刊：
影响因子：
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通讯作者：
O. Siegmund;J. Vallerga;P. Jelinsky;X. Michalet;S. Weiss
中科院分区：
文献类型：
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作者：
O. Siegmund;J. Vallerga;P. Jelinsky;X. Michalet;S. Weiss
地面高时间分辨率天文偏振测量、成像和生物时间分辨分子荧光寿命成像需要专门的探测器。结合联合收割机高空间分辨率成像与快速事件定时能力的光子计数探测器在这些应用中一直是一个重大的技术挑战。我们已经开发了一种高时间和空间分辨率，高通量的密封管微通道板检测器与电子读出作为这些应用的工具。该设计是基于一个25毫米直径的S20光电阴极，其次是一个微通道板堆栈，读出的交叉延迟线阳极与定时和成像电子。该探测器支持500 kHz全局计数率、10 kHz局部计数率、100 ps时序分辨率和40 /spl mu/m空间分辨率。我们描述了探测器的性能，以及与量子点和活细胞获得的成像结果。
Ground based high time resolution astronomical polarimetry, imaging, and biological time-resolved molecular fluorescence lifetime imaging require specialized detectors. Photon counting detectors that combine high spatial resolution imaging with fast event timing capability for these uses have been a significant technical challenge. We have developed a high-temporal and spatial resolution, high-throughput sealed tube microchannel plate detector with electronic readout as tool for these applications. The design is based on a 25 mm diameter S20 photocathode followed by a microchannel plate stack, read out by a cross delay line anode with timing and imaging electronics. The detector supports 500 kHz global count rate, 10 kHz local count rate, 100 ps timing resolution and 40 /spl mu/m spatial resolution. We describe the performance of the detector, as well as imaging results obtained with quantum dots and live cells.