A Psychoendocrine Study of Bereavement: Part I. 17‐Hydroxycorticosteroid Excretion Rates of Parents Following Death of Their Children from Leukemia

A Psychoendocrine Study of Bereavement: Part I. 17‐Hydroxycorticosteroid Excretion Rates of Parents Following Death of Their Children from Leukemia
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丧亲之痛的心理内分泌研究:第一部分:孩子死于白血病后父母的 17-羟基皮质类固醇排泄率

DOI:
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发表时间:
1972
影响因子:
3.3
通讯作者:
J. Mason
J. Mason
中科院分区:
医学3区
文献类型:
--
作者:
M. Hofer;C. Wolff;S. B. Friedman;J. Mason

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&NA;这项研究报告了40名父母在其子女死于白血病后2年内的17-羟皮质类固醇排泄率。总体组平均率保持不变,但这种明显的稳定性是儿童患病期间低比率的个体之间相互作用的结果,这些个体在随访回访NIH时显着增加了他们的比率,而那些在损失前具有高值的个体在损失后期间显示出显着下降的比率。在家中进行的少量收集显示出在家中比在NIH更低的值的总体趋势。这项对两种性质不同的关键生活情况下的受试者进行的长期研究表明,每个人的慢性肾上腺皮质排泄水平在即将失去对象的时期与失去对象后的哀悼时期相比可能会显着不同,并且差异的方向是个体受试者的重要特征。
&NA; This study reports 17‐hydroxycorticosteroid excretion rates of 40 parents during the 2 years following the death of their children from leukemia. Overall group mean rates remained unchanged, but this apparent stability was the result of an interaction between individuals with low rates during the child's illness, who significantly increased their rates at follow‐up return visits to NIH, and those with high values pre‐loss, who showed a significant decrease in rates during the post‐loss period. A smaller number of collections made at home showed a general trend toward lower values at home than at NIH. This long‐term study of subjects under two qualitatively different critical life situations indicates that each individual's chronic adrenocortical excretion levels can be significantly different during a period of impending object loss as compared to the period of mourning after that loss and that the direction of the difference is an important characteristic of the individual subject.