Relationship between functional magnetic resonance imaging-identified regions and neuronal category selectivity.
Relationship between functional magnetic resonance imaging-identified regions and neuronal category selectivity.
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DOI：
10.1523/jneurosci.5865-10.2011
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发表时间：
2011-08-24
期刊：
影响因子：
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通讯作者：
Ungerleider LG
中科院分区：
文献类型：
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作者：
Bell AH;Malecek NJ;Morin EL;Hadj-Bouziane F;Tootell RB;Ungerleider LG
Functional magnetic resonance imaging (fMRI) has been used extensively to identify regions in the inferior temporal (IT) cortex that are selective for categories of visual stimuli. However, comparatively little is known about the neuronal responses relative to these fMRI-defined regions. Here, we compared in non-human primates the distribution and response properties of IT neurons recorded within vs. outside fMRI regions selective for four different visual categories: faces, body-parts, objects, and places. Although individual neurons that preferred each of the four categories were found throughout the sampled regions, they were most concentrated within the corresponding fMRI region, decreasing significantly within 1–4 mm from the edge of these regions. Further, the correspondence between fMRI and neuronal distributions was specific to neurons that increased their firing rates in response to the visual stimuli, but not to neurons suppressed by visual stimuli, suggesting that the processes associated with inhibiting neuronal activity did not contribute strongly to the fMRI signal in this experiment.
