Maintenance electroconvulsive therapy for Parkinson's disease.
Maintenance electroconvulsive therapy for Parkinson's disease.
复制标题
帕金森病的维持性电休克治疗。
DOI：
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发表时间：
1997
期刊：
影响因子：
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通讯作者：
Langeveld Jh
中科院分区：
文献类型：
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作者：
D. Aarsland;Larsen Jp;O. Waage;Langeveld Jh
在两个严重的帕金森病（PD）患者的反应，左旋多巴下降，帕金森氏症的运动症状作出反应，急性和维持单侧电休克治疗（ECT）。例1在服用抗帕金森病药物治疗2个月和3个月后复发。再次复发后，他接受了维持性ECT治疗，并保持了13个月的良好状态。例2在ECT治疗一个疗程后4个月复发。急性和维持ECT诱导改善14个月。进一步复发的患者接受短暂的ECT治疗，随后接受维持性ECT治疗。在他们第一次ECT后的3年和4年，这两名患者的帕金森病运动症状仍然明显改善。神经心理学评估未提示ECT诱导的长期认知障碍。我们的结论是，维持ECT应考虑在PD患者复发后，有反应的初始过程的ECT。迫切需要进行对照研究。
In two patients with severe Parkinson's disease (PD) whose response to levodopa had decreased, the parkinsonian motor symptoms responded to acute and maintenance unilateral electroconvulsive therapy (ECT). Case 1 relapsed while taking antiparkinsonian medication 2 and 3 months after two brief courses of ECT. After another relapse, he received maintenance ECT and stayed well for 13 months. Case 2 relapsed 4 months after a course of ECT. Acute and maintenance ECT induced improvement for 14 months. Further relapses were treated with brief courses of ECT followed by maintenance ECT. Three and 4 years after their first ECT, the parkinsonian motor symptoms in these two patients are still markedly improved. Neuropsychological assessments did not suggest ECT-induced long-term cognitive impairment. We conclude that maintenance ECT should be considered in PD patients who relapse after having responded to an initial course of ECT. There is an urgent need for controlled studies.