A novel synthetic approach towards phytosiderophores:: Expeditious synthesis of nicotianamine and 2′-deoxymugineic acid

A novel synthetic approach towards phytosiderophores:: Expeditious synthesis of nicotianamine and 2′-deoxymugineic acid
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DOI:
10.1016/s0040-4039(97)10496-8
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发表时间:
1998-01-01
影响因子:
1.8
通讯作者:
Kitahara, T
Kitahara, T
中科院分区:
化学4区
文献类型:
--
作者:
Klair, SS;Mohan, HR;Kitahara, T

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通过多肽中间体,实现了一种合成烟胺、2′-脱氧氨基酸及相关植物铁载体的新方法。在酯官能团存在的情况下,通过转化为硫酰胺选择性还原酰胺和随后用兰尼镍进行脱硫是关键反应。1997爱思唯尔科学有限公司版权所有。
A short and a novel approach for synthesis of nicotianamine, 2'-deoxymugineic acid and related phytosiderophores has been achieved through peptide intermediates. Selective amide reduction in the presence of ester functionalities by conversion to thioamide and subsequent desulfurization with Raney nickel were employed as key reactions. (C) 1997 Elsevier Science Ltd. All rights reserved.