The metabolic derangements and treatment of diabetic ketoacidosis.
The metabolic derangements and treatment of diabetic ketoacidosis.
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DOI：
10.1056/nejm198307213090307
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发表时间：
1983-07
期刊：
影响因子：
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通讯作者：
Jeffrey S. Flier;Mary Jean Moore;D. Foster;J. Mcgarry
中科院分区：
文献类型：
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作者：
Jeffrey S. Flier;Mary Jean Moore;D. Foster;J. Mcgarry
糖尿病酮症酸中毒是糖尿病患者的常见病。确切的患病率尚不清楚，但在一个社区中，估计每1000例患者年中有13.4例糖尿病发作它仍然是一个严重的疾病，死亡率高达6%至10%。2,3在10岁以下儿童中，糖尿病酮症酸中毒占与糖尿病有关的死亡的70%死亡可能是由于直接归因于酮症酸中毒的紊乱，与疾病本身相关的并发症，或治疗引起的异常。因为相当大比例的死亡是…
Diabetic ketoacidosis is a common illness among patients with diabetes. The exact prevalence is unknown, but in one community the rate was estimated to be 13.4 episodes per 1000 patient-years in young persons with diabetes.1 It remains a serious event, with mortality rates as high as 6 to 10 per cent.2 , 3 In children under 10 years of age, diabetic ketoacidosis accounts for 70 per cent of diabetes-related deaths.4 Death may be due to derangements that are directly attributable to ketoacidosis, to complications associated with the illness itself, or to abnormalities induced by treatment. Because a substantial percentage of deaths is . . .