Olfactometry in fMRI studies: odor presentation using nasal continuous positive airway pressure.
Olfactometry in fMRI studies: odor presentation using nasal continuous positive airway pressure.
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功能磁共振成像研究中的嗅觉测量：使用鼻持续气道正压通气呈现气味。
DOI：
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发表时间：
2004
影响因子：
1.4
通讯作者：
G. Hajak
中科院分区：
文献类型：
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作者：
R. Popp;M. Sommer;Jürgen L. Müller;G. Hajak
我们描述了一种方法，用于产生和呈现嗅觉刺激的功能磁共振成像（fMRI）研究人类。嗅觉计基于空气稀释嗅觉测量法的原理，由鼻罩和鼻持续气道正压通气装置组成，这两种装置通常用于患有阻塞性睡眠呼吸暂停综合征的患者。该系统允许在线监测和记录受试者的呼吸模式。不同嗅觉条件之间的切换可以很容易地与吸入阶段同步，并由计算机控制。此外，切换发生迅速，没有任何光学，声学，热，或触觉线索的主题。作为实施的一个例子，我们提出了一个功能磁共振成像试验的嗅觉使用愉快和不愉快的气味刺激，以诱导不同的情感状态在健康受试者。相对便宜的嗅觉仪是可靠的，并允许恒定的气味浓度在固有的长期成像研究。
We describe a method for generating and presenting olfactory stimuli in functional magnetic resonance imaging (fMRI) studies for humans. The olfactometer is based on principles of air dilution olfactometry and consists of a nasal mask and a nasal Continuous Positive Airway Pressure device, both normally used for patients suffering from obstructive sleep apnea syndrome. The system allows online monitoring and recording of the subject's breathing pattern. Switching between different olfactory conditions can easily be synchronized with the inhalation phase and be controlled by a computer. Besides, switching occurs rapidly and without any optical, acoustic, thermal, or tactile cues for the subject. As an example of implementation we present a fMRI trial of olfaction using pleasant and unpleasant odor stimuli to induce different affective states in healthy subjects. The relatively inexpensive olfactometer is reliable and permits constant odor concentrations during the inherently prolonged imaging studies.
影响因子：
120.7
作者：
Crespo-Facorro, B;Paradiso, S;Hichwa, RD
通讯作者：
Hichwa, RD