Compressive, diametral tensile and biaxial flexural strength of cutting-edge calcium phosphate cements
Compressive, diametral tensile and biaxial flexural strength of cutting-edge calcium phosphate cements
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DOI：
10.1016/j.jmbbm.2016.03.028
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发表时间：
2016-07-01
影响因子：
3.9
通讯作者：
Persson, Cecilia
中科院分区：
文献类型：
--
作者：
Luo, Jun;Ajaxon, Ingrid;Persson, Cecilia
磷酸钙骨水泥（CPC）广泛应用于骨修复。目前存在两种主要类型的CPC，透钙磷石和磷灰石。该项目的目的是评估特别有前途的透钙磷石和磷灰石实验配方的机械性能，并与市售的透钙磷石和磷灰石基水泥（分别为chronOS（TM）Inject和Norian（R）SRS（R））进行比较，特别是首次评估这些水泥在潮湿和干燥条件下的径向拉伸强度和双轴弯曲强度。测试了水泥的孔隙率、抗压强度、径向抗拉强度和双轴弯曲强度。通过扫描电子显微镜对表面形貌进行了表征。用X-射线衍射评估相组成。结果发现，在所有载荷情况下，新型实验水泥均表现出比市售水泥更好的力学性能。实验透钙磷石水泥的抗压强度最高（干燥前为57.2 +/-6.5MPa，干燥后为69.5 +/-6.0MPa）。该水泥还显示出最高的湿径向拉伸强度（10.0 +/-0.8MPa）和湿双轴弯曲强度（30.7 +/-1.8MPa）。也是骨水泥的孔隙率最低（约为10%）。12%）。含水量的影响被发现取决于水泥类型，与一些水泥干燥后显示出较高的机械性能和干燥后没有差异。(C)2016作者爱思唯尔有限公司出版
Calcium phosphate cements (CPCs) are widely used in bone repair. Currently there are two main types of CPCs, brushite and apatite. The aim of this project was to evaluate the mechanical properties of particularly promising experimental brushite and apatite formulations in comparison to commercially available brushite- and apatite-based cements (chronOS (TM) Inject and Norian (R) SRS (R), respectively), and in particular evaluate the diametral tensile strength and biaxial flexural strength of these cements in both wet and dry conditions for the first time. The cements' porosity and their compressive, diametral tensile and biaxial flexural strength were tested in wet (or moist) and dry conditions. The surface morphology was characterized by scanning electron microscopy. Phase composition was assessed with X-ray diffraction. It was found that the novel experimental cements showed better mechanical properties than the commercially available cements, in all loading scenarios. The highest compressive strength (57.2 +/- 6.5 MPa before drying and 69.5 +/- 6.0 MPa after drying) was found for the experimental brushite cement. This cement also showed the highest wet diametral tensile strength (10.0 +/- 0.8 MPa) and wet biaxial flexural strength (30.7 +/- 1.8 MPa). It was also the cement that presented the lowest porosity (approx. 12%). The influence of water content was found to depend on cement type, with some cements showing higher mechanical properties after drying and some no difference after drying. (C) 2016 The Authors. Published by Elsevier Ltd.