Word-list generation deficits in dementia
Word-list generation deficits in dementia
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DOI：
10.1080/01688639608408304
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发表时间：
1996-12-01
影响因子：
2.2
通讯作者：
Brandt, J
中科院分区：
文献类型：
--
作者：
Barr, A;Brandt, J
为了评估阿尔茨海默病(AD)患者语义流畅性缺陷的特异性，我们将AD、亨廷顿病(HD)、血管性痴呆(VD)和健康对照组的表现与年龄相适应的对照组进行了比较，所有三组患者都表现出相对更严重的语义流畅性受损。痴呆症的严重程度并不影响这种关系。因此，语义引导流利性的更大脆弱性并不是AD所特有的，而是发生在其他痴呆症中。在AD、VD和HD患者中，语义记忆的组织和从长期存储中提取的缺陷似乎都是导致语义表现低于语音流畅性任务的原因之一。
To evaluate the specificity of the semantic fluency deficit in Alzheimer's disease (AD), we compared the performances of patients with AD, Huntington's disease (HD), vascular dementia (VD), and healthy control As compared to age-appropriate controls, all three patient groups demonstrated relatively more impaired semantic than phonemic fluency. Dementia severity did not affect this relationship. Thus, the greater vulnerability of semantically guided fluency is not specific to AD but occurs in other dementias as well. Deficits in both the organization of semantic memory and retrieval from long-term storage appear to contribute to the relatively poorer performance on semantic than phonemic fluency tasks observed in patients with AD, VD, and HD.