Diagnostic performance of initial enhancement analysis using ultra-fast dynamic contrast-enhanced MRI for breast lesions
Diagnostic performance of initial enhancement analysis using ultra-fast dynamic contrast-enhanced MRI for breast lesions
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DOI：
10.1007/s00330-018-5643-4
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发表时间：
2019-03-01
影响因子：
5.9
通讯作者：
Yamada, Kei
中科院分区：
文献类型：
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作者：
Goto, Mariko;Sakai, Koji;Yamada, Kei
ObjectivesTo评估的诊断价值和贡献BI-RADS分类的初始增强超快速DCE-MRI为区分恶性和良性breast lesions.MethodsThe机构审查委员会批准了这项研究，并从每个参与者获得书面知情同意书。对200名受试者共215个病变（147个恶性病变和68个良性病变）进行了用于初始增强分析的超快速DCE-MRI和常规MRI。使用常规MRI对增强病变进行BI-RADS分类。两个初始增强措施，增强时间（TTE）和最大斜率（MS），来自超快DCE-MRI。结果TTE和MS对乳腺肿块良恶性病变的诊断价值有显著性差异（P <0.05），对乳腺肿块良恶性病变的诊断价值有显著性差异（P <0.05），对乳腺肿块良恶性病变的诊断价值有显著性差异（P <0.05）。
ObjectivesTo assess the diagnostic value and contribution to BI-RADS categorisation of initial enhancement on ultra-fast DCE-MRI for differentiating malignant and benign breast lesions.MethodsThe institutional review board approved this study, and written informed consent was obtained from each participant. Both ultra-fast DCE-MRI for initial enhancement analysis and conventional MRI were performed on 200 subjects with a total of 215 lesions (147 malignant and 68 benign). BI-RADS categorisation of enhancing lesions was performed using the conventional MRI. Two initial enhancement measures, time to enhancement (TTE) and maximum slope (MS), were derived from the ultra-fast DCE-MRI. Diagnostic performance and the additional diagnostic value of adding TTE and MS to BI-RADS were evaluated.ResultsBoth TTE and MS showed significant differences between malignant and benign breast lesions in masses (TTE, p