Hepatic Encephalopathy
Hepatic Encephalopathy
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DOI：
10.1016/j.cld.2012.03.009
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发表时间：
2012-05-01
影响因子：
5.1
通讯作者：
Poordad, Fred
中科院分区：
文献类型：
--
作者：
Khungar, Vandana;Poordad, Fred
肝性脑病(HE)是一过性和可逆性的神经和精神功能障碍的连续体。它是肝病或门体分流患者认知功能受损或意识改变的可逆状态。在过去的几年里，对各种治疗HE的药物疗法进行了高质量的研究；随着更多数据的出现，人们希望HE将成为失代偿性肝病的一种更容易治疗的并发症。在此期间，除了继续提供目前对显性HE的治疗外，医生继续筛查轻度HE并及早治疗患者是很重要的。
Hepatic encephalopathy (HE) represents a continuum of transient and reversible neurologic and psychiatric dysfunction. It is a reversible state of impaired cognitive function or altered consciousness in patients with liver disease or portosystemic shunting. Over the last several years, high-quality studies have been conducted on various pharmacologic therapies for HE; as more data emerge, it is hoped that HE will become a more easily treated complication of decompensated liver disease. In the interim, it is important that physicians continue to screen for minimal HE and treat patients early in addition to continuing to provide current treatments of overt HE.