Electroencephalogram Features of Perioperative Neurocognitive Disorders in Elderly Patients: A Narrative Review of the Clinical Literature.
Electroencephalogram Features of Perioperative Neurocognitive Disorders in Elderly Patients: A Narrative Review of the Clinical Literature.
复制标题
老年患者围手术期神经认知障碍的脑电图特征：临床文献的叙述性回顾
DOI：
10.3390/brainsci12081073
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发表时间：
2022-08-13
期刊：
影响因子：
3.3
通讯作者：
Zhao, Guangchao
中科院分区：
文献类型：
--
作者：
Tang, Xuemiao;Zhang, Xinxin;Dong, Hailong;Zhao, Guangchao
关键词：
术后神经认知障碍（PND）是一种常见的术后并发症，尤其是在老年患者中。脑电监测是一种无创、高时空分辨率的监测技术，能准确反映围手术期脑功能的动态变化。目前的临床研究已经证实，全身麻醉期间α振荡的功率密度随着年龄的增长而降低，这被认为与老年人对PND的易感性增加有关。然而，关于EEG引导下的全身麻醉是否导致PND的发病率较低的证据仍然是矛盾的。这是麻醉深度的常见指标有限地来源于额叶中的EEG信号的原因之一。围手术期多通道EEG特征的变化有可能突出皮质下-皮质神经回路的隐匿性结构和功能异常。本文就多导脑电监测在老年PND发病预测中的应用作一综述。这些数据证实，EEG功率和远端脑区之间功能连接的异常变化与老年人PND的发病率和长期不良结局密切相关。
Postoperative neurocognitive disorder (PND) is a common postoperative complication, particularly in older patients. Electroencephalogram (EEG) monitoring, a non-invasive technique with a high spatial–temporal resolution, can accurately characterize the dynamic changes in brain function during the perioperative period. Current clinical studies have confirmed that the power density of alpha oscillation during general anesthesia decreased with age, which was considered to be associated with increased susceptibility to PND in the elderly. However, evidence on whether general anesthesia under EEG guidance results in a lower morbidity of PND is still contradictory. This is one of the reasons that common indicators of the depth of anesthesia were limitedly derived from EEG signals in the frontal lobe. The variation of multi-channel EEG features during the perioperative period has the potential to highlight the occult structural and functional abnormalities of the subcortical–cortical neurocircuit. Therefore, we present a review of the application of multi-channel EEG monitoring to predict the incidence of PND in older patients. The data confirmed that the abnormal variation in EEG power and functional connectivity between distant brain regions was closely related to the incidence and long-term poor outcomes of PND in older adults.
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影响因子：
5.7
作者：
Fritz BA;Kalarickal PL;Maybrier HR;Muench MR;Dearth D;Chen Y;Escallier KE;Ben Abdallah A;Lin N;Avidan MS
通讯作者：
Avidan MS
影响因子：
2.5
作者：
Gaskell, Amy;Pullon, Rebecca;Sleigh, Jamie
通讯作者：
Sleigh, Jamie
影响因子：
3
作者：
Acker L;Ha C;Zhou J;Manor B;Giattino CM;Roberts K;Berger M;Wright MC;Colon-Emeric C;Devinney M;Au S;Woldorff MG;Lipsitz LA;Whitson HE
通讯作者：
Whitson HE
影响因子：
9.8
作者：
Evered, Lisbeth A.;Chan, Matthew T., V;Short, Timothy G.
通讯作者：
Short, Timothy G.
DOI：
10.1213/xaa.0000000000000497
发表时间：
2017-06-15
期刊：
A & A CASE REPORTS
影响因子：
--
作者：
Kreuzer, Matthias;Whalin, Matthew K.;Garcia, Paul S.
通讯作者：
Garcia, Paul S.