EEG differences in children between eyes-closed and eyes-open resting conditions
EEG differences in children between eyes-closed and eyes-open resting conditions
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DOI：
10.1016/j.clinph.2009.08.006
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发表时间：
2009-10-01
影响因子：
4.7
通讯作者：
Brown, Christopher R.
中科院分区：
文献类型：
--
作者：
Barry, Robert J.;Clarke, Adam R.;Brown, Christopher R.
目的：最近对成人觉醒与激活的研究表明，从闭眼到睁眼静息基线条件下，皮肤电导水平（scl）升高，整体α水平降低。这项研究探讨了儿童是否也有类似的影响。方法：记录30例8 ~ 12岁儿童在平衡闭眼和睁眼休息状态下的脑电图活动；SCL作为唤醒指数进行测量。结果：闭眼状态下scl与平均α水平呈负相关，且从闭眼到睁眼显著升高。从闭眼到睁眼，头皮上δ、θ、α和β的平均绝对值都有所减少。除α波段外，其余波段均有明显的地形变化。结论：结果证实了使用平均α水平作为闭眼和睁眼条件下静息状态唤醒的测量。其他波段的局部变化表明，这些反映了激活的差异，而不是单纯的α波唤起的增加。意义：这项儿童研究证实了闭眼和睁眼的非阿尔法脑电图测量在平均功率水平和地形上的差异的普遍性，后者表明与视觉处理相关的大脑活动。在评估脑电图研究和选择不同范式的基线条件时，应考虑到这些差异。(C) 2009年国际临床神经生理学联合会。爱思唯尔爱尔兰有限公司出版。版权所有。
Objective: Recent work on arousal vs. activation in adults showed that skin conductance levels (SCLs) increased, and global alpha levels decreased, from eyes-closed to eyes-open resting baseline conditions. This study explored whether similar effects occur in children.Methods: EEG activity was recorded from 30 children aged 8-12 years during counterbalanced eyes-closed and eyes-open resting conditions; SCL was measured as an index of arousal.Results: SCLs were negatively correlated with mean alpha levels in the eyes-closed condition, and increased significantly from eyes-closed to eyes-open. Reductions were found in across-scalp mean absolute delta, theta, alpha, and beta from eyes-closed to eyes-open. Topographic changes were evident in all bands except alpha.Conclusions: Results confirm the use of mean alpha level as a measure of resting-state arousal under eyes-closed and eyes-open conditions. Focal changes in the other bands suggest that these reflect differences in activation, rather than the simple increase in arousal shown in alpha.Significance: This child study confirms the generality of eyes-closed vs. eyes-open non-alpha EEG measures differing in mean power levels and topography, the latter indicating brain activity related to visual processing. Such differences should be considered when evaluating EEG research, and in choosing baseline conditions for different paradigms. (C) 2009 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.