Correlation of nonsense sites in the lacI gene with specific codons in the nucleotide sequence
Correlation of nonsense sites in the lacI gene with specific codons in the nucleotide sequence
复制标题
lacI 基因中的无义位点与核苷酸序列中的特定密码子的相关性
作者：
Jeffrey H. Miller;C. Coulondre;P. Farabaugh
来自大肠杆菌lacI基因90个不同密码子的无义突变已与I基因核苷酸序列相关联。在80多个案例中，可以识别产生无义突变的特定密码子。序列分析表明，有14-16个碱基是通过串联双碱基变化产生的。
Nonsense mutations derived from 90 different codons in the lacI gene of Escherichia coli have been correlated with the I gene nucleotide sequence. In over 80 cases the specific codon which generates the nonsense mutation can be identified. The sequence shows that 14–16 sites arise through tandem double base changes.