Epidemiological investigation and antimicrobial susceptibility analysis of ureaplasma species and Mycoplasma hominis in outpatients with genital manifestations
Epidemiological investigation and antimicrobial susceptibility analysis of ureaplasma species and Mycoplasma hominis in outpatients with genital manifestations
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门诊有生殖器表现的解脲支原体及人型支原体流行病学调查及药敏分析
DOI：
10.1136/jclinpath-2014-202248
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发表时间：
2014-09-01
影响因子：
3.4
通讯作者：
Zhang, Jun
中科院分区：
文献类型：
--
作者：
Song, Tiejun;Ye, Aiqing;Zhang, Jun
目的了解杭州市2005 - 2013年门诊生殖道感染患者支原体和人型支原体的感染情况及耐药性。方法收集2689例女性和2336例男性生殖道感染患者的临床资料。结果女性患者支原体感染率为39.9%，人型支原体感染率为1.2%，合并感染率为13.4%，男性患者支原体感染率为18.8%，人型支原体感染率为0.4%，合并感染率为2.9%。此外，支原体（人型脲原体）的阳性率显著较高，女性（65.2%）和男性（27.3%）的16-20岁。支原体和人型支原体的耐药率较低（50%），2005 - 2013年明显上升。结论本研究提示，门诊年轻生殖道症状患者中支原体和人型支原体的阳性率较高，监测当地耐药情况对预防耐药菌株的发生至关重要。
Aims The aim of this study was to assess the prevalence and drug resistance of Ureaplasma species and Mycoplasma hominis in outpatients with genital manifestation from 2005 to 2013 in Hangzhou, China.Methods A total of 2689 female and 2336 male patients with various genital symptoms were included in this study. Species identification and antimicrobial susceptibility test were performed by using the mycoplasma IST-2 kit.Results The prevalence rate of Ureaplasma species was 39.9%, M hominis was 1.2% in female patients, and the coinfection rate was 13.4%; while in males, the prevalence rate of Ureaplasma species was 18.8%, M hominis was 0.4%, and the coinfection rate was 2.9%. Moreover, significantly high positive rates for mycoplasmas (Ureaplasma species M hominis) and were found in 16-20-year-old females (65.2%) and males (27.3%). Ureaplasma species and M hominis displayed relatively lower resistance rates (50%) and increased significantly from 2005 to 2013.Conclusions Our study indicates that high positive rates of Ureaplasma species and M hominis were found in young outpatients with genital symptoms, and monitoring the local drug resistance is critical for prevention of the occurrence of resistant strains.