EPIDEMIOLOGY OF VERTEBRAL FRACTURES IN WOMEN
EPIDEMIOLOGY OF VERTEBRAL FRACTURES IN WOMEN
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DOI：
10.1093/oxfordjournals.aje.a115204
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发表时间：
1989-05-01
影响因子：
5
通讯作者：
RIGGS, BL
中科院分区：
文献类型：
--
作者：
MELTON, LJ;KAN, SH;RIGGS, BL
对明尼苏达州罗切斯特市50岁及以上的女性进行年龄分层随机抽样，评估椎体骨折患病率。椎体骨折，包括楔形骨折、椎体压缩性骨折和椎体压缩性骨折是常见的，并且随着年龄的增长而增加。新椎骨骨折的估计发生率也随着年龄的增长而上升，在≤85岁的女性中达到每1，000人年29.6例。一个或多个椎体骨折的患病率也随着骨量的下降而增加，在双光子吸收法测量的脊柱骨密度小于0.6 g/cm 2的女性中达到42%。骨量和年龄对椎体骨折的风险有独立的影响，但“年龄”可能反映了骨质疏松症的其他表现。
Vertebral fracture prevalence was assessed in an age-stratified random sample of Rochester, Minnesota women aged 50 years and over. Vertebral fractures, including wedge and concavity as well as compression fractures, were common and increased with age. The estimated incidence of new vertebral fractures also rose with age, reaching 29.6 per 1,000 person-years in women aged ≤85 years. The prevalence of one or more vertebral fractures also increased with declining bone mass, reaching 42% in women with spinal bone mineral density less than 0.6 g/cm2by dual photon absorptiometry. Bone mass and age contributed independently to the risk of vertebral fracture, but “age” may reflect other manifestations of osteoporosis.