Indwelling ureteral stents: Evaluation of quality of life to aid outcome analysis
Indwelling ureteral stents: Evaluation of quality of life to aid outcome analysis
复制标题
DOI：
10.1089/089277901750134421
复制
发表时间：
2001-03-01
影响因子：
2.7
通讯作者：
Timoney, AG
中科院分区：
文献类型：
--
作者：
Joshi, HB;Stainthorpe, A;Timoney, AG
背景：输尿管支架会引起各种副作用。我们使用经过验证的问卷评估了支架患者的健康相关生活质量 (HRQoL)，并开发了新的支架症状（干预）特异性问卷 (SSQ)。 患者和方法：除了结构化文献回顾和深入访谈外，还使用通用问卷（SF-36 [N = 30]、EuroQol [N = 40] 和功能状态问卷 FSQ [N = 20]）和症状特异性问卷进行了前瞻性子研究（IPSS [N = 30] 和国际尿控协会 ICS [N = 30]）对支架原位和取出后进行的调查问卷。这些研究的结果为新的 SSQ 奠定了基础，该 SSQ 进行了试点测试 (N = 10) 和现场测试 (N = 20)，以便制定正式验证的调查问卷最终草案。 结果：定性研究发现了一系列问题。泌尿系统症状、疼痛、工作表现和总体健康状况是最重要的。大多数患者（80%）经历过令人烦恼的泌尿系统症状和与支架相关的疼痛。贮尿症状和尿失禁是影响生活质量的重要泌尿系统症状。多达40%的患者出现性功能障碍，支架对患者的整体健康产生了重大影响。现有措施均未评估完整影响。 SSQ 包括五个部分，涵盖泌尿系统症状、疼痛、性问题、一般健康状况和工作表现。初步结果显示其有效、可靠（α > 0.7），并且对支架取出后评分变化有反应（p < 0.05）。结论：留置输尿管支架与显着的发病率相关，导致 80% 患者的 HRQoL 降低。 SSQ 是一种可靠的干预专用工具，可作为评估支架影响的结果指标。
Background: Ureteral stents cause various side effects. We have evaluated health-related quality of life (HRQoL) in patients with stents using validated questionnaires and developed a new stent symptom (intervention)-specific questionnaire (SSQ).Patients and Methods: Along with structured literature review and in-depth interviews, prospective sub-studies were carried out using generic (SF-36 [N = 30], EuroQol [N = 40], and Functional Status Questionnaire FSQ [N = 20]) and symptom-specific (IPSS [N = 30] and International Continence Society ICS [N = 30]) questionnaires both with a stent in situ and after removal. The results of these studies formed the foundation for a new SSQ that was pilot tested (N = 10) and field tested (N = 20) in order to develop a final draft of the questionnaire that is formally validated.Results: The qualitative research identified a range of problems. Urinary symptoms, pain, work performance, and general health were the most important. Most patients (80%) experienced bothersome urinary symptoms and stent-related pain. Storage symptoms and incontinence were significant urinary symptoms affecting quality of life. As many as 40% of patients experienced sexual dysfunction, The stent had a significant impact on patients' general health. None of the existing measures evaluated the complete impact. The SSQ includes five sections covering urinary symptoms, pain, sexual matters, general health, and work performance. The preliminary results showed it to be valid, reliable (alpha > 0.7) and responsive to the change in scores (p < 0.05) after stent removal.Conclusions: Indwelling ureteral stents are associated with significant morbidity, resulting in a reduced HRQoL in 80% of patients. The SSQ is a reliable intervention-specific instrument that would be useful as an outcome measure to evaluate the impact of stents.