Enhancement of latent inhibition in rats with electrolytic lesions of the hippocampus.
Enhancement of latent inhibition in rats with electrolytic lesions of the hippocampus.
复制标题
DOI：
10.1037//0735-7044.109.2.366
复制
发表时间：
1995-04
影响因子：
1.9
通讯作者：
D. Purves;C. Bonardi;G. Hall
中科院分区：
文献类型：
--
作者：
D. Purves;C. Bonardi;G. Hall
两组大鼠——一组有海马电解损伤，另一组为假手术对照组——接受两种口味的味道厌恶调节。所有受试者都事先接受过对味道 A 的非强化暴露。潜在抑制在对味道 A 的厌恶感的获得速度慢于对味道 B 的反应中是明显的。海马损伤对获得非预先暴露的味道 B 没有影响，但产生了潜在抑制效应的显着增强。讨论了该结果与先前关于海马病变受试者中潜在抑制减弱的发现之间的对比。
Two groups of rats--1 with electrolytic lesions of the hippocampus and 1 consisting of sham-operated controls--received flavor-aversion conditioning with 2 flavors. All subjects had received prior nonreinforced exposure to Flavor A. Latent inhibition was apparent in slower acquisition of the aversion to Flavor A than to Flavor B. Hippocampal lesions had no effect on acquisition to the nonpreexposed Flavor B but produced a marked enhancement of the latent inhibition effect. The contrast between this result and previous findings of an attenuation of latent inhibition in subjects with hippocampal lesions is discussed.