Multipoint recognition of basic proteins at a membrane model.
Multipoint recognition of basic proteins at a membrane model.
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DOI：
10.1021/ja049191m
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发表时间：
2004-06
影响因子：
15
通讯作者：
Reza Zadmard;Markus Arendt;Thomas Schrader
中科院分区：
文献类型：
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作者：
Reza Zadmard;Markus Arendt;Thomas Schrader
由于其多价性，细胞表面识别实现了高效率和特异性。设计了一种由硬脂酸单分子膜和杯芳烃四膦酸酯受体分子组成的仿生模型。该系统能够在纳摩尔浓度下区分不同pI的蛋白质。
Cell surface recognition achieves high efficiency and specificity because of its polyvalent nature. A biomimetic model has been designed, which consists of a stearic acid monolayer with embedded calixarene tetraphosphonate receptor molecules. This system is able to distinguish between proteins of varying pI at nanomolar concentrations.