Palladium-Catalyzed Carboxylation of Activated Vinylcyclopropanes with CO2
Palladium-Catalyzed Carboxylation of Activated Vinylcyclopropanes with CO2
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DOI：
10.1021/acs.orglett.6b01231
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发表时间：
2016-06-03
期刊：
影响因子：
5.2
通讯作者：
Sato, Yoshihiro
中科院分区：
文献类型：
--
作者：
Mita, Tsuyoshi;Tanaka, Hiroyuki;Sato, Yoshihiro
以钯为催化剂，在CO2气氛下(1大气压)，活化的维里基环丙烷高产率地转化为相应的β，γ-不饱和羧酸。该反应的中间体被认为是一种亲核的ETA-烯丙基钯物种，它将由pi-烯丙基钯和ZnEt2(Upolung反应性)生成。
By using a palladium catalyst with ZnEt2, activated viriylcyclopropanes were successfully converted into the corresponding beta,gamma-unsaturated carboxylic acid's in high yields under a CO2 atmosphere (1 atm). The intermediate in this reaction is thought to be a nucleophilic eta-allylethylpalladium species, which would be produced from pi-allylpalladium and ZnEt2 (umpolung reactivity).