PHOTOREPAIR OF PYRIMIDINE DIMERS IN THE EPIDERMIS OF THE MARSUPIAL Monodelphis domestica *

PHOTOREPAIR OF PYRIMIDINE DIMERS IN THE EPIDERMIS OF THE MARSUPIAL Monodelphis domestica *
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有袋动物 Monodelphis Domestica 表皮中嘧啶二聚体的光修复*

DOI:
--
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发表时间:
1984
影响因子:
3.3
通讯作者:
R. Ley
R. Ley
中科院分区:
生物学3区
文献类型:
--
作者:
R. Ley

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摘要使用来自藤黄微球菌的损伤特异性核酸内切酶,在有袋类动物Monodelphis arctica的表皮中测量了紫外线辐射诱导的嘧啶二聚体在DNA中的诱导和命运。大约90%的二聚体丢失时,照射的动物进行光活化光180分钟。没有损失的二聚体检测时,动物在黑暗中保持了类似的时间。这些上皮细胞的能力,光修复嘧啶二聚体可以提供一个有用的整个动物系统中,以确定嘧啶二聚体在皮肤的光生物学反应的作用。
Abstract Induction and fate of ultraviolet radiation‐induced pyrimidine dimers in DNA have been measured in the epidermis of the marsupial, Monodelphis domestica, using damage‐specific endonucleases from Micrococcus luteus. Approximately 90% of the dimers are lost when irradiated animals are subjected to photoreactivating light for 180 min. No loss of dimers was detected when the animals were held for a similar period of time in the dark. The capacity of these epithelial cells to photorepair pyrimidine dimers may provide a useful whole animal system in which to determine the role of pyrimidine dimers in photobiological responses of the skin.
人类皮肤中嘧啶二聚体的形成。
DOI: 10.1111/j.1751-1097.1987.tb04758.x
发表时间: 1987
影响因子: 3.3
作者:
Freeman,SE;Gange,RW;Sutherland,JC;Sutherland,BM
通讯作者: Sutherland,BM
灰短尾负鼠 (Monodephis Domestica) 的护理和繁殖
DOI: --
发表时间: 1982
期刊: Laboratory animal science
影响因子: --
作者:
Fadem,BH;Trupin,GL;Maliniak,E;VandeBerg,JL;Hayssen,V
通讯作者: Hayssen,V