PRETERM PRELABOR AMNIORRHEXIS - INTRAUTERINE INFECTION AND INTERVAL BETWEEN MEMBRANE RUPTURE AND DELIVERY
PRETERM PRELABOR AMNIORRHEXIS - INTRAUTERINE INFECTION AND INTERVAL BETWEEN MEMBRANE RUPTURE AND DELIVERY
复制标题
DOI：
10.1136/fn.72.1.f43
复制
发表时间：
1995-01-01
影响因子：
4.4
通讯作者：
NICOLAIDES, KH
中科院分区：
文献类型：
--
作者：
CARROLL, SG;VILLE, Y;NICOLAIDES, KH
本研究旨在确定胎儿菌血症和羊水感染是否会缩短合并早产前羊水破裂的妊娠中隔膜破裂和临产之间的间隔。69例妊娠12-36周的早产前羊水破裂孕妇在期待治疗的情况下自发分娩。所有病例均行脐带穿刺术和羊水穿刺术，并对胎血和羊水进行需氧菌和厌氧菌培养。在胎血和羊水培养阴性的组（第1组）中，从羊水破裂到分娩的中位间隔为41天（范围1-161），羊水破裂时的胎龄与分娩间隔呈负相关。在胎血阴性但羊水培养阳性的组（第2组）中，胎儿破裂至分娩间隔的中位数为9天（范围1-37），胎血培养阳性组（第3组）间隔2天（范围1-5）这些发现表明，合并早产、早产前子宫破裂和胎儿菌血症的妊娠在胎膜早破后5天内发生自然分娩。破裂，如果不发生分娩，则不太可能发生感染。
This study aimed to determine if fetal bacteraemia and amniotic fluid infection at the time of membrane rupture reduces the interval between membrane rupture and the onset of labour in pregnancies complicated by preterm prelabour amniorrhexis.Sixty nine pregnancies with preterm prelabour amniorrhexis at 12-36 weeks' gestation that were managed expectantly had spontaneous onset of labour. In all cases cordocentesis and amniocentesis were performed and fetal blood and amniotic fluid were cultured for aerobic and anaerobic bacteria. In the group with negative fetal blood and amniotic fluid cultures (group 1) the median interval from amniorrhexis to delivery was 41 days (range 1-161) and there was an inverse correlation between gestational age at amniorrhexis and delivery interval. In the group with negative fetal blood but positive amniotic fluid cultures (group 2) the median amniorrhexis to delivery interval was nine days (range 1-37), and in the group with positive fetal blood cultures (group 3) the interval was two days (range 1-5).These findings suggest that pregnancies complicated by preterm prelabour amniorrhexis and fetal bacteraemia undergo spontaneous labour within five days of membrane rupture, and if labour does not occur then infection is unlikely.