Dynamins and BAR Proteins-Safeguards against Cancer.
Dynamins and BAR Proteins-Safeguards against Cancer.
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DOI:
10.1615/critrevoncog.v20.i5-6.160
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发表时间:
2015
影响因子:
--
通讯作者:
Hinshaw JE
中科院分区:
文献类型:
--
作者:
Sundborger AC;Hinshaw JE
Dynamins and BAR proteins are crucial in a wide variety of cellular processes for their ability to mediate membrane remodeling, such as membrane curvature and membrane fission and fusion. In this review, we highlight dynamins and BAR proteins and the cellular mechanisms that are involved in the initiation and progression of cancer. We specifically discuss the roles of these proteins in endocytosis, endo-lysosomal trafficking, autophagy, and apoptosis as these processes are all tightly linked to membrane remodeling and cancer.