Bacterial microleakage and pulp inflammation associated with various restorative materials
Bacterial microleakage and pulp inflammation associated with various restorative materials
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DOI：
10.1016/s0109-5641(01)00072-0
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发表时间：
2002-09-01
期刊：
影响因子：
5
通讯作者：
Cox, CF
中科院分区：
文献类型：
--
作者：
Murray, PE;Hafez, AA;Cox, CF
目标：许多修复材料据称可成功防止细菌微渗漏并最大程度地减少牙髓炎症。然而，有关材料体内性能相互比较的信息有限。本研究的目的是评估和比较九种修复材料放置在非暴露猴蛀牙中时的牙髓反应。方法：将 279 个标准化非暴露 V 类蛀牙制备成颊侧牙本质。使用以下类别的多种材料修复蛀牙：氧化锌丁香酚 (ZnOE)、氢氧化钙 [Ca(OH)(2)]、磷酸锌 (ZP)、树脂改性玻璃离聚物 (RMGI)、复合树脂 (CR)、键合汞齐 (BA)、古塔胶 (GP)、复合聚合物和硅酸盐。根据 ISO 指南，以短期、中期和长期间隔收集牙髓组织并进行评估；采用组织形态计量分析、Spearman's rho 和方差分析统计。纸浆反应根据 FDI、ISO 和 ADA 标准进行分类。使用麦凯染色剂检测细菌。结果：发现牙髓炎症与修复体周围的细菌微渗漏相关（p小于或等于0.0001）。研究发现，不同修复材料的细菌微渗漏频率有所不同（p 小于或等于 0.0001）。按防止细菌微泄漏从最好到最差的顺序排列； RMGI (100%)、BA (88%)、ZnOE (86%)、CR (80%)、GP (64%)、Ca(OH)(2) (58%)、复合体 (42%)、硅酸盐 (36%) 和 ZP (0%)。 意义：防止炎症活动引起的细菌微渗漏和牙髓损伤的最有效的修复材料是 RMGI、BA、ZnOE 和 CR 修复体。 (C) 2002 年牙科材料学会。由爱思唯尔科学有限公司出版。保留所有权利。
Objectives: Many restorative materials are claimed to be successful in preventing bacterial microleakage and minimizing pulp inflammation. However, information regarding the in vivo performance of materials in comparison with each other is limited. The aim of this study was to evaluate and compare the pulp response of nine restorative materials when placed in non-exposed monkey cavities.Methods: 279 standardized non-exposed Class V cavities, were prepared into buccal dentin. Cavities were restored with a number of materials in the following categories: Zinc oxide eugenol (ZnOE), Calcium hydroxide [Ca(OH)(2)], zinc phosphate (ZP), Resin-modified glass ionomer (RMGI), Composite resin (CR), Bonded amalgam (BA), Gutta-percha (GP), Compomer and Silicate. Pulp tissues were collected and evaluated at short, intermediate and long-term intervals according to ISO guidelines; employing histomorphometric analysis, Spearman's rho and ANOVA statistics. Pulp responses were categorized according to FDI, ISO and ADA standards. Bacteria were detected using McKay stains.Results: Pulp inflammation was found to be correlated to bacterial microleakage around the restoration (pless than or equal to0.0001). The frequency of bacterial microleakage was found to vary between restorative materials (p less than or equal to0.0001). In rank order of preventing bacterial microleakage from best to the worst; RMGI (100%), BA (88%), ZnOE (86%), CR (80%), GP (64%), Ca(OH)(2) (58%), compomer (42%), silicate (36%) and ZP (0%).Significance: The most effective restorative materials to prevent bacterial microleakage and pulp injury from inflammatory activity were RMGI, BA, ZnOE and CR restorations. (C) 2002 Academy of Dental Materials. Published by Elsevier Science Ltd. All rights reserved.