Immunoreactive parathyroid hormone after volume change in normo- and hypotensive hemodialysis patients.
Immunoreactive parathyroid hormone after volume change in normo- and hypotensive hemodialysis patients.
复制标题
正常和低血压血液透析患者容量变化后的免疫反应性甲状旁腺激素。
作者：
B. Heintz;H. Mann;H. Kierdorf;F. Königs;K. Nelson;R. Kirsten;N. Heicke;D. Wieland;U. Gladziwa;H. Sieberth
本文研究了血液透析过程中血容量减少对终末期肾功能衰竭正常和过度透析患者循环免疫反应性甲状旁腺激素（PTH）的影响，并与血压和心率的变化进行了相关性分析。在透析过程中，PTH的血浆浓度没有变化，血压正常，而PTH显着增加，在有效血管内容量减少25%的过程中，血压下降的患者。在血液透析过程中使用作者的血红蛋白测量系统连续测量血容量。两组的血容量减少相当。结果提示，血液透析过程中PTH的分泌可能在血液透析过程中血液动力学不稳定中起作用。
The effects of reduced blood volume during hemodialysis on circulating immunoreactive parathyroid hormone (PTH) were determined in relation to changes in blood pressure and heart rate in normo- and hypotensive patients with end stage renal failure. During dialysis the plasma concentration of PTH did not change in normotensives, while PTH increased significantly in patients with a fall in blood pressure during a 25% reduction in effective intravascular volume. The blood volume was measured continuously during hemodialysis using the authors' hemoglobin measurement system. The decrease in blood volume in both groups was comparable. The results suggest that secretion of PTH during hemodialysis may play a role in hemodynamic instability during hemodialysis.