Effects of vitamin E supplementation on some pregnancy health indices: a randomized clinical trial
Effects of vitamin E supplementation on some pregnancy health indices: a randomized clinical trial
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DOI：
10.2147/ijgm.s20107
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发表时间：
2011-01-01
影响因子：
2.3
通讯作者：
Navali, Nazli
中科院分区：
文献类型：
--
作者：
Bastani, Parvin;Hamdi, Kobra;Navali, Nazli
目的：关于维生素E在正常妊娠中的作用的现有证据不足。本研究评估了维生素E补充剂对妊娠期健康指标的潜在益处。方法：采用1：2加权简单随机技术，将104名符合条件的孕妇分配到接受维生素E和168名妇女（对照）不接受药物。接受治疗的妇女从妊娠14周到妊娠结束时，胶囊中含有400 IU维生素E。结果：发现包括母亲年龄在内的背景变量在研究组之间分布相似。产妇和围产期结局（包括Apgar评分和出生体重）的发生率在两组之间没有显著差异。先兆子痫发生在1%的治疗妇女与1.78%的对照women.Conclusion：给予补充维生素E从妊娠中期并没有出现影响妊娠结局和先兆子痫发生的风险。
Objective: Available evidence about the role of supplementary vitamin E in normal pregnancy is inadequate. This study assessed the potential benefit of vitamin E supplementation on some pregnancy health indices.Methods: A 1: 2 weighted simple randomization technique was used to allocate 104 eligible pregnant women to receive vitamin E and 168 women (control) not to receive the drug. Treated women received capsules containing 400 IU vitamin E from week 14 of gestation to the end of the pregnancy.Results: Background variables including maternal age were found to be similarly distributed between the study groups. The rate of maternal and perinatal outcomes including Apgar score and birth weight did not differ significantly between groups. Preeclampsia occurred in 1% of treated women vs 1.78% of control women.Conclusion: Giving supplemental vitamin E from the second trimester of pregnancy did not appear to affect the risk of pregnancy outcomes and occurrence of preeclampsia.