Single Molecular Layer of Silk Nanoribbon as Potential Basic Building Block of Silk Materials
Single Molecular Layer of Silk Nanoribbon as Potential Basic Building Block of Silk Materials
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单分子层丝纳米带作为丝材料的潜在基本构件
DOI：
10.1021/acsnano.8b03943
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发表时间：
2018-12-01
期刊：
影响因子：
17.1
通讯作者：
Zhang, Yaopeng
中科院分区：
文献类型：
--
作者：
Niu, Qianqian;Peng, Qingfa;Zhang, Yaopeng
在这项研究中，平均厚度为0.4 nm的新生蚕丝纳米带（SNRs）的提取从天然蚕丝脱胶丝（DS）的部分溶解在氢氧化钠（NaOH）/尿素溶液在-12 ℃。在这种温和的处理中，溶剂不能完全破坏纳米纤维结构，但所选择的条件会影响所得SNR的尺寸。丝模型的分子动力学模拟表明，丝素蛋白链之间的氢键断裂所需的平均力的潜力比β-片层之间的货车范德华相互作用的潜力大40%，允许剥离处理。结果发现，所得到的SNRs包含一个单一的β-折叠层和无定形丝素蛋白分子，这可以被认为是由分级结构组成的DS的基本构建块。所展示的用于提取具有单个β-片层高度的BSNRs的技术可以提供用于产生更强和更坚韧的丝基材料和/或在用于各种应用的材料中增加功能性和耐久性的有用途径。基于信噪比的层次结构模型可以更好地理解丝基材料的结构与性能之间的关系。
In this study, nascent silk nanoribbons (SNRs) with an average thickness of 0.4 nm were extracted from natural silkworm silk by partially dissolving degummed silk (DS) in sodium hydroxide (NaOH)/urea solution at -12 degrees C. In this gentle treatment, the solvent could not destroy the nanofibrillar structure completely, but the chosen conditions would influence the dimensions of resulting SNRs. Molecular dynamics simulations of silk models indicated that the potential of mean force required to break hydrogen bonds between silk fibroin chains was 40% larger than that of van der Waals interactions between beta-sheet layers, allowing the exfoliating treatment. It was found that the resulting SNRs contained a single beta-sheet layer and amorphous silk fibroin molecules, which could be considered as the basic building block of DS consisting of hierarchical structures. The demonstrated technique for extracting ultrathin SNRs having the height of a single beta-sheet layer may provide a useful pathway for creating stronger and tougher silk-based materials and/or adding functionality and durability in materials for various applications. The hierarchical structure model based on SNRs may afford more insight into the structure and property relationship of fabricating silk-based materials.