A Globally Available Internet-Based Patient Survey of Pemphigus Vulgaris: Epidemiology and Disease Characteristics
A Globally Available Internet-Based Patient Survey of Pemphigus Vulgaris: Epidemiology and Disease Characteristics
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DOI：
10.1016/j.det.2011.03.016
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发表时间：
2011-07-01
影响因子：
2.4
通讯作者：
Sinha, Animesh A.
中科院分区：
文献类型：
--
作者：
Gupta, Vibha K.;Kelbel, Theodore E.;Sinha, Animesh A.
作者开发了一种可在全球范围内使用的匿名、基于网络的调查工具，并收集了171名寻常型天疱疮(PV)患者的数据，以收集与人口统计学不同人群中广泛的一组临床参数有关的流行病学数据。结果表明，女性占多数，疾病发病在生命的第五个十年，PV与患者及其家庭成员中的甲状腺疾病和1型糖尿病有很强的相关性。大多数患者有单纯黏膜皮损或皮肤粘膜皮损的病史，但许多患者只报告皮肤皮损，没有先前或同时存在的粘膜皮损，特别是在非北美PV人群中。
The authors developed an anonymous, Web-based survey instrument available globally, and collected data from 171 pemphigus vulgaris (PV) patients to assemble epidemiologic data pertaining to an extensive set of clinical parameters in demographically diverse populations. The results showed female predominance, prevalent onset of disease in the fifth decade of life, and a strong correlation of PV with thyroid disease and type 1 diabetes in patients and family members. Most patients have a history of either mucosal-only or mucocutaneous lesions, but numerous patients self-report cutaneous lesions only, without previous or concurrent mucosal lesions, especially in the non North American PV population.