Comparative Studies on the Characteristic Fatty Acid Profiles of Four Different Chinese Medicinal Sargassum Seaweeds by GC-MS and Chemometrics.

Comparative Studies on the Characteristic Fatty Acid Profiles of Four Different Chinese Medicinal Sargassum Seaweeds by GC-MS and Chemometrics.
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GC-MS和化学计量学比较四种中药海藻特征脂肪酸谱

DOI:
10.3390/md14040068
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发表时间:
2016-03-29
期刊:
影响因子:
5.4
通讯作者:
Guan H
Guan H
中科院分区:
医学2区
文献类型:
--
作者:
Chen Z;Xu Y;Liu T;Zhang L;Liu H;Guan H

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马尾藻海藻在中国有着丰富的生物量,长期以来一直被用作草药和食物。它们的特征脂肪酸(FA)谱和相关的促进心血管健康(CVH)的潜在功能尚未被系统地研究。本研究采用GC-MS联用技术对四种药用马尾藻的脂肪酸组成进行了分析。采用主成分分析方法对四种药用马尾藻进行了鉴别,并对两个正品种海藻和两个民间药种海千进行了潜在结构的正交投影判别分析。在所调查的所有藻类中,主要的SFA和MUFA分别是棕榈酸和硬脂酸,而主要的PUFA是亚油酸、花生四烯酸和二十碳五烯酸。羊栖菜和羊栖菜的多不饱和脂肪酸含量较高。关于CVH,所有研究物种,特别是羊栖菜,都表现出令人满意的水平,如PUFA/SFA比值和n-6/n-3比值。每个物种都有一个独特的FA特征,并受到明显的区别。评估了潜在的关键FA标记(在两个中国官方物种之间和两个民间物种之间)。本研究提供了四种中药材马尾藻的特征脂肪酸组成及其促进CVH的相关潜在功能。
Sargassum seaweeds produce abundant biomass in China and have long been used as herbal medicine and food. Their characteristic fatty acid (FA) profiles and related potential function in promoting cardiovascular health (CVH) have not been systematically investigated. In this study, FA profiles of four medicinal Sargassum were characterized using GC-MS. Principal component analysis was used to discriminate the four medicinal Sargassum, and orthogonal projection to latent structures discriminant analysis was carried out between the two official species HAI ZAO and between the two folk medicine species HAI QIAN. In all of the algae investigated, the major SFA and MUFA were palmitic and stearic acid, respectively, while the major PUFAs were linoleic, arachidonic, and eicosapentaenoic acid. S. fusiforme and S. horneri had higher concentrations of PUFAs. With respect to CVH, all of the studied species, particularly S. fusiforme, exhibited satisfactory levels such as PUFA/SFA ratio and n-6/n-3 ratio. Each species possesses a unique FA profile and is discriminated clearly. Potential key FA markers (between the two Chinese official species, and between the two folk species) are assessed. The study provides characteristic fatty acid profiles of four Chinese medicinal Sargassum and their related potential function in promoting CVH.