Frequency of Ear Symptoms and Hearing Loss in Ichthyosis: A Pilot Survey Study
Frequency of Ear Symptoms and Hearing Loss in Ichthyosis: A Pilot Survey Study
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DOI：
10.1111/pde.12292
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发表时间：
2014-05-01
影响因子：
1.5
通讯作者：
Liang, Marilyn G.
中科院分区：
文献类型：
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作者：
Huang, Jennifer T.;Mallon, Kaitlin;Liang, Marilyn G.
鱼鳞病包括由角膜化损伤引起的多种皮肤状况。虽然耳部结构可能受到影响，但从未调查过鱼鳞病患者的耳部相关症状。在这项初步调查研究中，我们的目的是确定鱼鳞病患者耳部症状、听力损失和相关医疗干预的频率。我们的第二个目的是根据年龄组比较这些项目的出现频率。使用Redcap开发了一项在线调查，并在鱼鳞病和相关皮肤类型基金会网站上发布了6个月的在线调查。鱼鳞病患者或患者的父母被要求完成调查。数据分析排除了角膜炎-鱼鳞病-耳聋综合征患者和完成项目少于两个的调查。135个独特的调查被用于数据分析。在所有参与者中，80%报告耳朵瘙痒，66%报告听力障碍，29%报告频繁耳痛，28%的听力测试结果异常，16%使用助听器。在88名报告听力有问题的参与者中，24人（27.3%）从未看过听力专家。18岁以上的参与者（74%,57/77）比18岁及以下的参与者（53%,31/58;p=0.02）报告有听力障碍。其他耳部症状和听力损失的频率在年龄组之间无统计学差异。耳部瘙痒、耳痛和听力损失是所有年龄组各种形式鱼鳞病患者的重要问题。早期诊断和干预可以改善鱼鳞病患者的生活质量。
Ichthyoses comprise a heterogeneous array of skin conditions resulting from impairment of cornification. Although ear structures can be affected, ear-related symptoms have never been investigated in patients with ichthyosis. In this pilot survey study, our aim was to determine the frequency of ear symptoms, hearing loss, and related medical interventions in patients with ichthyosis. Our secondary aim was to compare the frequency of these items according to age group. An online survey using Redcap was developed and posted online on the Foundation for Ichthyosis and Related Skin Types website for 6months. Patients or parents of patients with ichthyosis were asked to complete the survey. Data analysis excluded patients with keratitis-ichthyosis-deafness syndrome and surveys that had fewer than two completed items. One hundred thirty-five unique surveys were used for data analysis. Of all participants, 80% reported ear pruritus, 66% reported trouble hearing, 29% reported frequent ear pain, 28% had abnormal hearing test results, and 16% had used hearing aids. Of the 88 participants who reported trouble hearing, 24 (27.3%) had never been to a hearing specialist. Significantly more participants older than 18years of age (74%, 57/77) reported trouble hearing than participants age 18 years and younger (53%, 31/58; p=0.02). The frequencies of other ear symptoms and hearing loss were not statistically significantly different between the age groups. Ear pruritus, ear pain, and hearing loss are important concerns in patients with all forms of ichthyosis in all age groups. Early diagnosis and intervention may improve the quality of life of patients with ichthyosis.