Primary pericardial mesothelioma presenting as pericardial constriction: a case report

Primary pericardial mesothelioma presenting as pericardial constriction: a case report
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DOI:
10.1136/heart.90.1.e4
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发表时间:
2004-01-01
期刊:
影响因子:
5.7
通讯作者:
Large, S
Large, S
中科院分区:
医学1区
文献类型:
--
作者:
Suman, S;Schofield, P;Large, S

文献摘要

被引文献

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一名19岁的男性,有6个月的胸痛、呼吸困难和嗜睡病史,超声心动图发现左心室扩张伴少量心包积液。尝试了雷米普利和一个疗程的类固醇,但连续超声心动图显示持续增厚的心包和缓慢发展的收缩特征。在电脑断层上,发现一个巨大的纵膈腔肿块包裹住心脏,沿着有主动脉旁及旁淋巴结肿大。右心导管检查显示四个腔室压力相等。他不断恶化的临床状况导致心包切除术。组织学证实为原发性心包间皮瘤。患者在手术后不久死亡。
A 19 year old man presented with a six month history of chest pain, dyspnoea, and lethargy and was found on an echocardiogram to have a dilated left ventricle with a small pericardial effusion. Ramipril and a course of steroids were tried but serial echocardiograms showed a persistently thickened pericardium and slowly developing features of constriction. On computed tomography, a large mediastinal mass encasing the heart, along with para-aortic and paratracheal lymphadenopathy, was found. Right heart catheter studies showed equal pressures in all four chambers. His deteriorating clinical condition led to a pericardiectomy. Histology confirmed primary pericardial mesothelioma. The patient died soon after surgery.