ANALYSIS OF ELECTRONIC CIGARETTE CARTRIDGES, REFILL SOLUTIONS, AND SMOKE FOR NICOTINE AND NICOTINE RELATED IMPURITIES
ANALYSIS OF ELECTRONIC CIGARETTE CARTRIDGES, REFILL SOLUTIONS, AND SMOKE FOR NICOTINE AND NICOTINE RELATED IMPURITIES
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DOI：
10.1080/10826076.2011.572213
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发表时间：
2011-01-01
影响因子：
1.3
通讯作者：
Westenberger, Benjamin J.
中科院分区：
文献类型：
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作者：
Trehy, Michael L.;Ye, Wei;Westenberger, Benjamin J.
本研究的目的是测定电子烟弹、用于填充烟弹的液体以及使用电子烟装置产生的烟雾中的尼古丁和尼古丁相关杂质，即可替宁、麦斯明、新烟草碱、假木贼碱和β-二烯烟碱。对HPLC法进行了验证。含尼古丁产品的样品通过互联网从NJOY、Smoking Everywhere、CIXI和约翰逊溪购买。电子烟装置购自NJOY、Smoking Everywhere和CIXI。测试结果发现，（1）某些制造商的尼古丁含量标签不准确，（2）电子烟的“烟雾”中存在尼古丁，以及（3）发现烟弹和笔芯中的尼古丁相关杂质含量因电子烟制造商而异。
The objective of this study was to determine nicotine and the nicotine related impurities, that is, cotinine, myosmine, anatabine, anabasine, and beta-nicotyrine, in electronic cigarette cartridges, the liquid used to fill the cartridges, and from smoke generated using the electronic cigarette devices. An HPLC method was validated for the determination. Samples of nicotine containing products were purchased via the internet from NJOY, Smoking Everywhere, CIXI, and Johnson Creek. Electronic cigarette devices were purchased from NJOY, Smoking Everywhere, and CIXI. The results from the testing found that (1) the nicotine content labeling was not accurate with some manufacturers, (2) nicotine is present in the "smoke" from electronic cigarettes, and (3) nicotine related impurities contents in cartridges and refills were found to vary by electronic cigarette manufacturer.