Neural correlates of decision variables in parietal cortex
Neural correlates of decision variables in parietal cortex
复制标题
DOI：
10.1038/22268
复制
发表时间：
1999-07-15
期刊：
影响因子：
64.8
通讯作者：
Glimcher, PW
中科院分区：
文献类型：
--
作者：
Platt, ML;Glimcher, PW
决策理论提出，人类和动物通过评估每个可能反应的相对价值来决定在给定情况下做什么，这种评估可以部分地从每个行动将导致收益的概率和预期收益的大小来计算，在这里，我们表明，增益（或奖励）猴子可以期望从眼球运动反应中意识到的调节外侧顶内区神经元的活动，灵长类动物大脑皮层的一个区域，被认为是将视觉信号转化为眼球运动命令的区域。我们还表明，这些神经元的活动对特定反应将导致增益的概率很敏感，当动物可以在两种替代反应之间自由选择时，受试者做出的选择和该区域的神经元激活都与动物可以从每个响应中预期的相对增益量相关。我们的数据表明，决策理论模型可以为研究感觉和行动之间的神经过程提供一个强大的新框架。
Decision theory proposes that humans and animals decide what to do in a given situation by assessing the relative value of each possible response, This assessment can be computed, in part, from the probability that each action will result In a gain and the magnitude of the gain expected, Here we show that the gain (or reward) a monkey can expect to realize from an eye-movement response modulates the activity of neurons in the lateral intraparietal area, an area of primate cortex that is thought to transform visual signals into eye-movement commands, We also show that the activity of these neurons is sensitive to the probability that a particular response will result in a gain, When animals can choose freely between two alternative responses, the choices subjects make and neuronal activation in this area are both correlated with the relative amount of gain that the animal can expect from each response. Our data indicate that a decision-theoretic model may provide a powerful new framework for studying the neural processes that intervene between sensation and action.