Incidence and descriptive features of testicular cancer among United States whites, blacks, and hispanics, 1973–1982
Incidence and descriptive features of testicular cancer among United States whites, blacks, and hispanics, 1973–1982
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1973-1982 年美国白人、黑人和西班牙裔睾丸癌的发病率和描述性特征
作者：
M. Spitz;Joanne G. Sider;E. Pollack;H. K. Lynch;G. Newell
这是一份描述性流行病学报告，基于 1973 年至 1982 年向美国国家癌症研究所的监测、流行病学和最终结果 (SEER) 项目报告的美国和波多黎各居民中发生的 3000 多起睾丸癌病例。白人男性的发病率明显高于新墨西哥州西班牙裔、黑人和波多黎各西班牙裔男性，加权风险比为分别为 1.36、4.62 和 4.80。发病率的种族差异在极端年龄时最不明显。尽管组织学亚型的分布在不同种族阶层之间没有差异，但形态表达与诊断时的年龄有关。每个族群的儿童期（<15 岁）右侧肿瘤受累占主导地位，但在最年长的年龄组或隐睾中出现的肿瘤中则不然。未婚男性似乎比已婚男性患非精原细胞瘤睾丸癌的风险更大。使用可比地理区域的数据对种族长期趋势进行分析表明，所有三个种族群体的年轻男性发病率持续上升。不同种族阶层的比率差异和描述参数的同质性之间的对比表明环境病因学中定量差异而非定性差异的影响。
This is a descriptive epidemiologic report based on over 3000 incident testicular cancer cases occurring among residents of the US and Puerto Rico, as reported to the Surveillance, Epidemiology and End Results (SEER) program of the National Cancer Institute for the years 1973 through 1982. White men had significantly higher incidence rates than their New Mexico Hispanic, black, and Puerto Rican Hispanic counterparts with weighted risk ratios of 1.36, 4.62, and 4.80, respectively. Ethnic differences in incidence were least evident at the extremes of age. Although the distribution of histologic subtypes did not differ across ethnic strata, morphologic expression was related to age at diagnosis. There was a predominance of right‐sided tumor involvement in each ethnic group in childhood (<15 years of age), but not in the oldest age categories or among tumors presenting in cryptorchid testes. Never married men appeared to be at greater risk of developing nonseminoma testicular cancer than their married counterparts. Analysis of ethnic secular trends, using data from comparable geographic areas, showed a consistent increase in incidence among young men for all three ethnic groups. The contrast between the rate differences and the homogeneity of descriptive parameters across ethnic strata suggest the impact of quantitative rather than qualitative differences in environmental etiology.