Capecitabine-induced lichenoid drug eruption: a case report.
Capecitabine-induced lichenoid drug eruption: a case report.
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卡培他滨诱发的苔藓样药疹：病例报告。
作者：
J. Gehlhausen;M. Strausburg;M. Aouthmany;T. Katona;M. Turner
卡培他滨是一种以5-氟尿嘧啶为基础的化疗药物，广泛用于实体肿瘤的治疗，尤其是结直肠癌和乳腺肿瘤。卡培他滨在自然界中的一些最常见的副作用，包括手足综合征(掌底红斑感觉障碍)。文献中的一些报告将卡培他滨的使用与光敏性类固醇皮疹联系起来。在此，我们提出了一例卡培他滨引起的转移性乳腺癌老年女性患者的苔藓样皮疹病例，并讨论了我们的发现与先前报道的卡培他滨引起的其他皮肤病变的关系。
Capecitabine is a 5-fluorouracil basedchemotherapeutic drug widely used in the treatmentof solid tumors, especially colorectal and breast. Someof the most common side effects of capecitabine arecutaneous in nature, including hand-foot syndrome(palmar-plantar erythrodysesthesia). Several reports inthe literature link capecitabine use with photosensitivelichenoid eruptions. Herein, we present a case ofcapecitabine-induced lichenoid eruption in an elderlyfemale with metastatic breast cancer and discuss ourfindings in relationship to previously reported cases ofthis and other capecitabine-induced skin pathologies.