The impact of co-infections on fish: a review.

The impact of co-infections on fish: a review.
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DOI:
10.1186/s13567-016-0383-4
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发表时间:
2016-10-04
影响因子:
4.4
通讯作者:
El-Matbouli M
El-Matbouli M
中科院分区:
农林科学2区
文献类型:
--
作者:
Kotob MH;Menanteau-Ledouble S;Kumar G;Abdelzaher M;El-Matbouli M

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共同感染在自然界中非常常见,当宿主同时或继发感染两种或两种以上不同的病原体时,就会发生共同感染,从而使两种或两种以上的传染性病原体在同一宿主中一起活跃。共同感染具有根本性的影响,可以改变不同鱼类疾病的病程和严重程度。然而,在鱼类等水生动物中,共同感染效应仍然受到有限的审查,并且关于这一主题的可用数据仍然很少。在混合感染期间,鱼类对不同病原体的敏感性可能会发生变化,从而导致鱼类突然爆发。在这篇综述中,我们着重于在同源或异源病原体共感染过程中发生的增效和拮抗相互作用。我们提出了一个简明的总结关于目前的知识关于鱼的共同感染。需要更多的研究来更好地了解鱼类在混合感染期间的免疫反应,因为这些可能对鱼类疾病控制计划和疫苗接种新策略的发展产生重要影响。
Co-infections are very common in nature and occur when hosts are infected by two or more different pathogens either by simultaneous or secondary infections so that two or more infectious agents are active together in the same host. Co-infections have a fundamental effect and can alter the course and the severity of different fish diseases. However, co-infection effect has still received limited scrutiny in aquatic animals like fish and available data on this subject is still scarce. The susceptibility of fish to different pathogens could be changed during mixed infections causing the appearance of sudden fish outbreaks. In this review, we focus on the synergistic and antagonistic interactions occurring during co-infections by homologous or heterologous pathogens. We present a concise summary about the present knowledge regarding co-infections in fish. More research is needed to better understand the immune response of fish during mixed infections as these could have an important impact on the development of new strategies for disease control programs and vaccination in fish.
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