HIV-positive persons who inject drugs experience poor health outcomes and unmet needs for care services.
HIV-positive persons who inject drugs experience poor health outcomes and unmet needs for care services.
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注射吸毒的艾滋病毒阳性者健康状况不佳，护理服务需求得不到满足。
DOI：
10.1080/09540121.2020.1826396
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发表时间：
2021-09
期刊：
影响因子：
1.7
通讯作者：
Shouse RL
中科院分区：
文献类型：
--
作者：
Dasgupta S;Tie Y;Lemons-Lyn A;Broz D;Buchacz K;Shouse RL
比较艾滋病毒阳性注射吸毒者（注射吸毒者）和艾滋病毒阳性非注射吸毒者之间的健康和临床结果的社会决定因素对于了解差异并为艾滋病毒预防和护理工作提供信息至关重要；然而，缺乏具有全国代表性的估计。医疗监测项目收集了 2015 年至 2018 年美国确诊艾滋病毒成年人的访谈和医疗记录数据。在艾滋病毒阳性吸毒者 (N=340) 和不注射吸毒的艾滋病毒阳性者 (N=11,475) 中，我们报告了加权百分比和患病率以及预测边际平均值，以比较各组之间的差异 (P<.05)。与临床结果的关联根据年龄、种族/民族和性别进行了调整。 HIV 阳性吸毒者更有可能无家可归（29.1% vs. 8.1%）和被监禁（18.3% vs. 4.9%）。 HIV 阳性吸毒者不太可能继续接受 HIV 护理（aPR：0.85 [95% CI：0.77–0.94]），并且更有可能出现较差的 HIV 结果、护理服务需求未得到满足（aPR：1.50 [1.39–1.61]）、寻求非常规护理以及遭受医疗保健歧视（aPR：1.42 [1.17–1.73]）。加强干预措施，支持（1）在高水平监禁和住房不稳定的情况下提供连续性护理，（2）早期开始接受抗逆转录病毒治疗和坚持治疗，以及（3）药物治疗和减少伤害计划以限制传播风险，可能会改善艾滋病毒阳性吸毒者的结局。
Comparison of social determinants of health and clinical outcomes between HIV-positive persons who inject drugs (PWID) and HIV-positive persons who do not inject drugs is essential to understanding disparities and informing HIV prevention and care efforts; however, nationally representative estimates are lacking. Interview and medical record data were collected for the Medical Monitoring Project during 2015–2018 among U.S. adults with diagnosed HIV. Among HIV-positive PWID (N=340) and HIV-positive persons who do not inject drugs (N=11,475), we reported weighted percentages and prevalence ratios with predicted marginal means to compare differences between groups (P<.05). Associations with clinical outcomes were adjusted for age, race/ethnicity, and gender. HIV-positive PWID were more likely to be homeless (29.1% vs. 8.1%) and incarcerated (18.3% vs. 4.9%). HIV-positive PWID were less likely to be retained in HIV care (aPR: 0.85 [95% CI: 0.77–0.94]), and were more likely to have poor HIV outcomes, have unmet needs for care services (aPR: 1.50 [1.39–1.61]), seek non-routine care, and experience healthcare discrimination (aPR: 1.42 [1.17–1.73]). Strengthening interventions supporting (1) continuity of care given high levels of incarceration and housing instability, (2) early ART initiation and adherence support, and (3) drug treatment and harm reduction programs to limit transmission risk may improve outcomes among HIV-positive PWID.
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影响因子：
4.9
作者：
Bradford, Judith B.;Coleman, Sharon;Cunningham, William
通讯作者：
Cunningham, William
DOI：
10.1097/qai.0000000000001242
发表时间：
2017-02-01
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
--
作者：
Colasanti J;Stahl N;Farber EW;Del Rio C;Armstrong WS
通讯作者：
Armstrong WS
DOI：
10.1056/nejmoa1600693
发表时间：
2016-09-01
期刊：
The New England journal of medicine
影响因子：
--
作者：
Cohen MS;Chen YQ;McCauley M;Gamble T;Hosseinipour MC;Kumarasamy N;Hakim JG;Kumwenda J;Grinsztejn B;Pilotto JH;Godbole SV;Chariyalertsak S;Santos BR;Mayer KH;Hoffman IF;Eshleman SH;Piwowar-Manning E;Cottle L;Zhang XC;Makhema J;Mills LA;Panchia R;Faesen S;Eron J;Gallant J;Havlir D;Swindells S;Elharrar V;Burns D;Taha TE;Nielsen-Saines K;Celentano DD;Essex M;Hudelson SE;Redd AD;Fleming TR;HPTN 052 Study Team
通讯作者：
HPTN 052 Study Team
DOI：
10.1097/00126334-200107010-00006
发表时间：
2001-07-01
期刊：
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
影响因子：
--
作者：
Lucas, GM;Cheever, LW;Moore, RD
通讯作者：
Moore, RD
影响因子：
33.9
作者：
Golden, Matthew R.;Lechtenberg, Richard;Buskin, Susan E.
通讯作者：
Buskin, Susan E.