FUNCTIONAL MAGNETIC-RESONANCE-IMAGING OF SENSORY AND MOTOR CORTEX - COMPARISON WITH ELECTROPHYSIOLOGICAL LOCALIZATION
FUNCTIONAL MAGNETIC-RESONANCE-IMAGING OF SENSORY AND MOTOR CORTEX - COMPARISON WITH ELECTROPHYSIOLOGICAL LOCALIZATION
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DOI：
10.3171/jns.1995.83.2.0262
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发表时间：
1995-08-01
影响因子：
4.1
通讯作者：
ALLISON, T
中科院分区：
文献类型：
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作者：
PUCE, A;CONSTABLE, RT;ALLISON, T
使用1.5Tesla磁共振系统进行功能磁共振成像，以定位感觉运动皮质。6名神经学正常受试者通过轴向梯度回波图像进行了研究，其中包括一项运动任务和一项或多项感觉任务：1)电刺激正中神经；2)在大鱼际区持续刷牙；3)将压缩空气脉冲吹过手掌和手指。在中央沟或中央沟附近观察到增强的MR信号，与初级感觉和运动皮质的位置一致。对4名患者进行了回声平面成像序列和运动和感觉任务的研究。3例患者继发于感觉运动皮质病变所致的局灶性难治性癫痫。功能性磁共振成像上所见的激活与由诱发电位和电刺激确定的感觉运动区的位置是一致的。功能性磁共振成像为感觉运动皮质的定位和功能评估提供了一种有用的无创方法。
Functional magnetic resonance (MR) imaging was performed using a 1.5-tesla MR system to localize sensorimotor cortex. Six neurologically normal subjects were studied by means of axial gradient-echo images with a motor task and one or more sensory tasks: 1) electrical stimulation of the median nerve; 2) continuous brushing over the thenar region; and 3) pulsed now of compressed air over the palm and digits. An increased MR signal was observed in or near the central sulcus, consistent with the location of primary sensory and motor cortex.Four patients were studied using echo planar imaging sequences and motor and sensory tasks. Three patients had focal refractory seizures secondary to a lesion impinging on sensorimotor cortex. Activation seen on functional MR imaging was coextensive with the location of the sensorimotor area determined by evoked potentials and electrical stimulation. Functional MR imaging provides a useful noninvasive method of localization and functional assessment of sensorimotor cortex.