Community-Associated Methicillin-Resistant Staphylococcus aureus: Trends in Case and Isolate Characteristics from Six Years of Prospective Surveillance
Community-Associated Methicillin-Resistant Staphylococcus aureus: Trends in Case and Isolate Characteristics from Six Years of Prospective Surveillance
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DOI：
10.1177/003335490912400312
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发表时间：
2009-05-01
影响因子：
3.3
通讯作者：
Lynfield, Ruth
中科院分区：
文献类型：
--
作者：
Como-Sabetti, Kathryn;Harriman, Kathleen H.;Lynfield, Ruth
目标. 2000年，明尼苏达州卫生部（MDH）对社区相关的耐甲氧西林金黄色葡萄球菌（CA-MRSA）实施了积极的哨点监测。对2000-2005年的数据进行分析，以确定病例特征、脉冲场类型（PFT）和抗菌药物敏感性（包括诱导型克林霉素耐药（ICR））的趋势。2000年，在为住院病人和门诊病人服务的12个医院实验室启动了积极的哨点监测。审查患者病历，以确定其是否符合CA-MRSA的流行病学病例标准;从符合这些标准的患者中获得分离株。MDH公共卫生实验室进行了脉冲场凝胶电泳分型和抗菌药物敏感性测试，包括ICR。M RSA病例中CA的比例从11%上升到33%（p
Objectives. In 2000, the Minnesota Department of Health (MDH) implemented active, sentinel site surveillance for community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA). Data from 2000-2005 were analyzed to determine trends in case characteristics, pulsed-field types (PFTs), and antimicrobial susceptibilities including inducible clindamycin resistance (ICR).Methods. Active sentinel site surveillance was initiated in 2000 at 12 hospital laboratories that served inpatients and outpatients. Patient medical records were reviewed to determine if they met the epidemiologic case criteria for CA-MRSA; isolates were obtained from patients meeting these criteria. The MDH Public Health Laboratory performed pulsed-field gel electrophoresis subtyping and antimicrobial susceptibility testing, including ICR.Results. The proportion of M RSA cases classified as CA increased from 11% to 33% (p