Context binding and hallucination predisposition
Context binding and hallucination predisposition
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DOI：
10.1016/j.paid.2008.08.016
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发表时间：
2008-12-01
影响因子：
4.3
通讯作者：
Paulik, Georgie
中科院分区：
文献类型：
--
作者：
Badcock, Johanna C.;Chhabra, Saruchi;Paulik, Georgie
精神分裂症和目前的幻听患者在上下文绑定和故意抑制方面表现出缺陷。幻觉也会出现在普通人群中，表明存在潜在的因果机制的连续性，然而，这些经历也可能不同(例如，在频率上)，表明病因学上的一些差异。这项研究的目的是检查健康年轻人的幻觉经历的频率，并评估上下文约束困难是否表现出高度容易产生幻觉的个体的特征。615名本科生完成了Launay-Slade幻觉量表的修订版，其中包括对幻觉经历频率的评估，并从高(n=25)和低(n=27)得分者中抽取了亚样本。使用语音位置绑定任务评估上下文记忆能力。结果表明，LSHS-R得分高的人产生幻觉的频率比之前报道的精神分裂症患者要少得多。此外，没有观察到情境记忆绑定的组间差异，也没有观察到幻觉频率和情境绑定困难之间的任何关联。幻觉的连续性模型可能忽略了普通人群与精神病患者在幻觉体验上的一些重要差异。皇冠版权所有(C)2008由爱思唯尔有限公司出版。保留所有权利。
Patients with Schizophrenia and current auditory hallucinations exhibit a combination of deficits in context binding and intentional inhibition. Hallucinations also occur in the general population suggesting an underlying continuity of causal mechanisms, however, these experiences may also differ (e.g., in frequency), indicating some differences in aetiology. The aim of this study was to examine the frequency of hallucinatory experiences in healthy young adults and to assess whether difficulties in context binding characterize individuals highly predisposed to hallucinations. A modified version of the Launay-Slade hallucination scale-revised, including an assessment of the frequency of hallucination experiences, was completed by 615 undergraduates from which sub-samples of high (n = 25) and low (n = 27) scorers were drawn. Context memory ability was assessed using a voice-location binding task. The results showed that the frequency of hallucinations in high LSHS-R scorers was much less than that previously reported for individuals with schizophrenia. Furthermore, no group differences in context memory binding were observed, nor any association between hallucination frequency and context binding difficulties. The continuity model of hallucinations may overlook some important differences in hallucinatory experiences in the general population versus psychosis. Crown Copyright (C) 2008 Published by Elsevier Ltd. All rights reserved.