Construction of photo-responsive micelles from azobenzene-modified hyperbranched polyphosphates and study of their reversible self-assembly and disassembly behaviours
Construction of photo-responsive micelles from azobenzene-modified hyperbranched polyphosphates and study of their reversible self-assembly and disassembly behaviours
复制标题
偶氮苯修饰超支化聚磷酸盐光响应胶束的构建及其可逆自组装和解体行为研究
DOI：
10.1039/c2nj20882b
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发表时间：
2012-01-01
影响因子：
3.3
通讯作者：
Ji, Jian
中科院分区：
文献类型：
--
作者：
Chen, Chao-Jian;Liu, Gong-Yan;Ji, Jian
Photo-responsive micelles with reversible self-assembly and disassembly behaviours were constructed via the supramolecular host-guest interaction of beta-cyclodextrin (beta-CD) and an amphiphilic azobenzene-containing hyperbranched polymer (denoted HPHEEP-Azo). The polymer was prepared through the carboxylation of hydroxyl groups in hyperbranched polyphosphate (HPHEEP-OH) with succinic anhydride and the subsequent esterification reaction with 4-hydroxyazobenzene. Dynamic light scattering (DLS) and transmission electron microscopy (TEM) measurements reveal that HPHEEP-Azo can self-assemble into spherical micelles with an average diameter of 169.9 nm in aqueous solution. The critical micelle concentration (CMC) of the micelles is 0.013 mg mL(-1). After addition of beta-CD into the micellar solution, the micelles dissociated gradually upon increasing the addition amount of beta-CD. Irradiation experiments show that reversible self-assembly and disassembly behaviours can be controlled by irradiating with UV and visible light. These photo-responsive micelles self-assembled from hyperbranched polymers might have great potential in various practical applications such as controlled drug release.
