Does caffeine bind to metal ions?
Does caffeine bind to metal ions?
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DOI：
10.1016/s0308-8146(03)00244-9
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发表时间：
2004-01-01
期刊：
影响因子：
8.8
通讯作者：
Abbasoglu, R
中科院分区：
文献类型：
--
作者：
Kolayli, S;Ocak, M;Abbasoglu, R
咖啡因是一种高消费的茶和咖啡组分，测定了咖啡因与Ca、Mg、Fe、Zn、Pb、Mn、Co和Cr金属离子的络合形成能力。金属离子-咖啡因络合物的金属选择的结合常数进行了测定。将结果与已知的金属离子-EDTA络合物的稳定常数进行比较，EDTA以其高金属结合能力而闻名。采用亚铁嗪参比法研究了咖啡因的铁螯合活性，并与EDTA进行了比较。结果表明，咖啡因的结合常数为29.6，22.4的络合物形成能力非常小。与EDTA相比，对Ca、Mg、Fe、Zn、Pb、Mn、Co和Cr金属离子的吸附量分别为59、396、55、9.3、83和592 M-1。还发现咖啡因的铁螯合活性为6%，这被认为与EDTA相比相当低。(C)2003爱思唯尔有限公司。保留所有权利。
The complex formation capacity of caffeine, a highly-consumed tea and coffee component, was determined for Ca, Mg, Fe, Zn, Pb, Mn, Co and Cr metal ions. The binding constants of metal ion-caffeine complexes for the metals chosen were determined spectrophotometrically. The results were compared with the known stability constants of metal ion-EDTA complexes, EDTA being known for its high metal binding capacity. Furthermore, iron chelating activity of caffeine, using the ferrozine reference method, was studied and compared with that of EDTA. The results showed very little complex formation capacity of caffeine with binding constants of 29.6, 22.4. 59, 396, 55, 9.3, 83 and 592 M-1 for Ca, Mg, Fe, Zn, Pb, Mn, Co and Cr metal ions, respectively, in contrast to that of EDTA. The iron chelating activity of caffeine was also found to be 6%, which was considered to be quite low compared with EDTA. (C) 2003 Elsevier Ltd. All rights reserved.