Functional outcomes after chemoradiotherapy of laryngeal and pharyngeal cancers.
Functional outcomes after chemoradiotherapy of laryngeal and pharyngeal cancers.
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DOI:
10.1007/s11912-012-0216-1
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发表时间:
2012-04
影响因子:
4.7
通讯作者:
Lewin, Jan S.
中科院分区:
文献类型:
--
作者:
Hutcheson, Katherine A.;Lewin, Jan S.
Organ preservation regimens that combine chemotherapy and radiotherapy (chemoradiotherapy) are increasingly used as the primary treatment of laryngeal and pharyngeal cancers. Meta-analytic data show a survival benefit with combined modality therapy, but the functional sequelae can be significant. Dysphagia is recognized as a common and often devastating late effect of chemoradiotherapy. This review examines functional outcomes after chemoradiotherapy for laryngeal and pharyngeal cancers, with a particular emphasis on dysphagia. Topics examined include the burden of dysphagia after chemoradiation, pathophysiology of dysphagia, baseline functioning, recommendations to improve long-term function, and voice outcomes.
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期刊:
ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES
影响因子:
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通讯作者:
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