Grid laser treatment of macular edema in macular branch retinal vein occlusion
Grid laser treatment of macular edema in macular branch retinal vein occlusion
复制标题
网格激光治疗黄斑分支视网膜静脉阻塞黄斑水肿
DOI：
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发表时间：
2004
影响因子：
1.4
通讯作者：
G. Ravalico
中科院分区：
文献类型：
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作者：
M. B. Parodi;S. Saviano;L. Bergamini;G. Ravalico
目的：黄斑分支视网膜静脉阻塞（MBRVO）是视网膜分支静脉阻塞的一个亚组，其中阻塞限于引流黄斑区域的一部分的小静脉血管。本研究的目的是评估格栅激光治疗MBRVO黄斑水肿的疗效。方法：对77例新发MBRVO患者进行为期24个月的前瞻性研究。眼睛被随机分配到网格激光治疗组和对照组。随访期间记录视力、黄斑水肿和血管造影特征等临床参数。结果：两组患者在随访3个月（p<0.001）和随访1年（p<0.005）后视力均显著提高。在两年对照时未观察到额外改善。两组间无统计学差异。结论：格栅状激光治疗黄斑水肿并不能改善MBRVO的视力预后。这表明，中央感光细胞的突然缺血性损伤，而不是黄斑水肿是永久性视力下降的主要因素。
Aim: Macular branch retinal vein occlusion (MBRVO) is a subgroup of branch retinal vein occlusion in which the occlusion is limited to a small venous vessel draining a sector of the macular region. The present study aims to evaluate the efficacy of grid laser treatment for macular edema in MBRVO. Methods: 77 Patients with MBRVO of recent onset were prospectively studied during a 24 month period. Eyes were randomly assigned to a grid laser treatment group and to a control group. Clinical parameters such as visual acuity, presence of macular edema and angiographic features were recorded during the follow-up period. Results: Visual acuity increased significantly in both groups after 3 months of follow-up (p<0.001) and after 1 year of follow-up (p<0.005). No additional improvement was noted at the two year control. There was no statistical difference between the two groups. Conclusions: The visual prognosis of MBRVO is not improved after grid laser treatment of macular edema. This suggests that sudden ischemic damage to central photoreceptors rather than macular edema is the main factor for permanent visual acuity reduction.