MOTHER OFFSPRING INTERACTION AND PUP DEVELOPMENT IN GENETICALLY DEAF MICE
MOTHER OFFSPRING INTERACTION AND PUP DEVELOPMENT IN GENETICALLY DEAF MICE
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DOI：
10.1007/bf01073113
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发表时间：
1987-09-01
影响因子：
2.6
通讯作者：
POPULIN, R
中科院分区：
文献类型：
--
作者：
DAMATO, FR;POPULIN, R
通过使用GFF品系的遗传性耳聋(dN/dN)和听力正常(+/+)小鼠，研究了幼鼠发出的超声波叫声对母体行为的影响。分析了未寄养和交叉寄养幼崽的行为和感觉-运动发育，以及母亲的行为。失聪的幼崽发出的超声波信号比听力正常的幼崽要少。交叉培养过程减少了正常幼崽发出的发声量，从而强调了母性行为对幼崽超声波交流的强化作用。聋哑人和听力正常的母亲对自己的幼崽的母性行为没有差异。然而，与亲生母亲抚养的幼崽相比，交叉养育的幼崽得到的母性照顾更少，这种影响在听力正常的母亲抚养的失聪幼崽中更加明显，反之亦然。母亲和幼崽的耳聋似乎都与运动活动增加有关，这可能是为了抵消它们在母子关系中的听觉障碍。此外，失聪幼崽的体重比正常幼崽增长得更快，这一能力受到养育父母的基因的影响。总体而言，这些数据可能表明，失聪小鼠的母性行为已经独立于幼鼠发出的超声波刺激。失聪小鼠的其他生物行为特征表明，与听力正常的小鼠相比，这些小鼠在母子互动中发挥了更积极的作用。
The role of ultrasonic calls emitted by pups on maternal behavior has been investigated by using genetically deaf (dn/dn) and normal-hearing (+/+) mice of the GFF strain. The behavior and the sensory-motor development of unfostered and cross-fostered pups, as well as the behavior of the mothers, was analyzed. Deaf pups emitted fewer ultrasonic calls than pups with normal hearing. The cross-fostering procedure decreased the amount of vocalizations produced by normal pups, thus stressing the reinforcement effect of maternal behavior on pups'' ultrasonic communication. No difference in maternal behavior emerged between deaf and normal-hearing mothers toward their pups. However, cross-fostered pups received less maternal care than pups raised by their natural mothers, this effect being more evident in deaf pups reared by mothers with normal hearing, than vice versa. Deafness, in both mothers and pups, seemed to be associated with increased locomotor activity, possibly to offset their auditory handicap in mother-offspring relationships. Furthermore, deaf pups showed a faster gain in weight than normal pups, this capability being affected by the genotype of the rearing parent. On the whole, these data could suggest that maternal behavior in deaf mice has became independent of ultrasonic stimuli emitted by the pups. Other biobehavioral characteristics of deaf mice indicate a more active role played by these pups in mother-offspring interaction in comparison with pups with normal hearing.