Evolutionary dynamics of extranuclear genes
Evolutionary dynamics of extranuclear genes
复制标题
核外基因的进化动力学
DOI：
10.1017/s0016672300021753
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发表时间：
1983
影响因子：
1.5
通讯作者：
M. Slatkin
中科院分区：
文献类型：
--
作者：
N. Takahata;M. Slatkin
我们研究了核外基因的进化动力学，考虑了简单种类的选择、两种遗传模式和细胞内基因组的多样性。特别注意在核外基因组中积累有利或有害的突变。由于基因组的多样性和非孟德尔分离导致的世代内漂移促进了有利突变的固定，并防止了有害突变的积累。我们还表明，父亲的贡献程度对这一比例几乎没有影响，但相反，基因组的结构和传播方式都有很大的差异。这些结果与已知的核外基因组是一致的。
We studied the evolutionary dynamics of extranuclear genes taking into account simple kinds of selection, two modes of inheritance and the multiplicity of genomes within a cell. Particular attention was paid to the accumulation of advantageous or deleterious mutations in an extranuclear genome. Within-generation drift due to multiplicity of genome and non-Mendelian segregation promotes the fixation of advantageous mutations and prevents deleterious mutations from accumulating. We show also that the extent of paternal contribution makes little difference in the rate, but, in contrast, the configuration of the genome and the mode of transmission both makes a large difference. These results are compatible with what is known about extranuclear genomes.
DOI：
10.1073/pnas.77.11.6715
发表时间：
1980-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
--
作者：
GILES, RE;BLANC, H;WALLACE, DC
通讯作者：
WALLACE, DC