Primary affective disorder criteria and the endogenous-reactive distinction.
Primary affective disorder criteria and the endogenous-reactive distinction.
复制标题
原发性情感障碍标准和内源性反应性区别。
DOI：
10.1001/archpsyc.1980.01780200065007
复制
发表时间：
1980
影响因子：
--
通讯作者：
D. Charney
中科院分区：
文献类型：
--
作者：
J. Nelson;D. Charney
76例患者住院期间的一年的抑郁发作，没有其他精神疾病的既往史进行了回顾性评估，使用原发性情感障碍的标准。由两名未参与患者治疗且对出院诊断、住院过程和治疗反应不知情的评定者进行症状评定。根据抑郁综合征是自主的还是对环境变化的反应，将患者分为“内源性”或“反应性”。92%的内源性抑郁症患者和45%的反应性抑郁症患者符合明确的原发性情感障碍的标准。我们认为，原发性情感障碍的标准定义一个异质性组的患者内源性反应的区别。价值的标准，将确定一个同质的内源性抑郁状态的组进行了讨论。确定内源性抑郁症患者的主要情感障碍症状是精神变化、自责和注意力下降。
Seventy-six patients hospitalized during the course of one year with a depressive episode and without prior history of other psychiatric illness were evaluated retrospectively using the primary affective disorder criteria. Symptom ratings were made by two raters uninvolved in the treatment of the patient and blind to the discharge diagnosis, hospital course, and treatment response. The patients were designated "endogenous" or reactive" based on whether the depressive syndrome was autonomous or responsive to environmental changes. Ninety-two percent of the patients with endogenous depression and 45% of those with reactive depression met the criteria for definite primary affective disorder. We suggest that the primary affective disorder criteria define a heterogeneous group of patients with respect to the endogenous-reactive distinction. The value of criteria that would identify a homogeneous group with an endogenous depressive state is discussed. The primary affective disorder symptoms that did identify patients with endogenous depression were psychomotor change, self-reproach, and decreased concentration.