A Simple and Disposable Sampler for Inhalable Aerosol.
A Simple and Disposable Sampler for Inhalable Aerosol.
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可吸入气溶胶的简单且一次性的采样器。
DOI：
10.1093/annhyg/mev065
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发表时间：
2016-03
期刊：
影响因子：
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通讯作者：
Volckens J
中科院分区：
文献类型：
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作者：
L'Orange C;Anderson K;Sleeth D;Anthony TR;Volckens J
可吸入气溶胶危害的个人采样技术受到采样器成本和复杂性问题的限制；这些问题限制了执业卫生学家对一些采样器的采用和使用。因此，尽管已知可吸入气溶胶危害对健康有影响，但通常只对一小部分有风险的工作人员进行个人接触评估。为了解决当前可吸入气溶胶采样技术的局限性，开发了一种一次性可吸入气溶胶采样器，并在实验室进行了评估。与现有的技术相比，新的采样器的设计更便宜，使用更简单。采样器包括融合到采样过滤器的轻质内部胶囊。这种胶囊过滤器组件允许包含沉积在内壁和入口的颗粒，从而最大限度地减少了在进行重量分析时清洗或擦拭内部采样盒的需要。在粒径为9.5 ~ 89.5 μm的低速风洞中测试了采样效率和壁面损失。将结果与提出的低速吸入性标准以及IOM采样器上公布的数据进行比较。对滤波器的权重稳定性和平衡时间进行了评价，因为这些因素会影响设计的实用性。对新采样器的初步测试表明，该采样器与IOM和所提出的低速吸入性曲线吻合良好。在高温条件下，胶囊和过滤器组件在制造后25小时内达到平衡。达到平衡后，胶囊-过滤器组合在0.01mg范围内稳定。
The state-of-the-art for personal sampling for inhalable aerosol hazards is constrained by issues of sampler cost and complexity; these issues have limited the adoption and use of some samplers by practicing hygienists. Thus, despite the known health effects of inhalable aerosol hazards, personal exposures are routinely assessed for only a small fraction of the at-risk workforce. To address the limitations of current technologies for inhalable aerosol sampling, a disposable inhalable aerosol sampler was developed and evaluated in the laboratory. The new sampler is designed to be less expensive and simpler to use than existing technologies. The sampler incorporates a lightweight internal capsule fused to the sampling filter. This capsule-filter assembly allows for the inclusion of particles deposited on the internal walls and inlet, thus minimizing the need to wash or wipe the interior sampling cassette when conducting gravimetric analyses. Sampling efficiency and wall losses were tested in a low-velocity wind tunnel with particles ranging from 9.5 to 89.5 μm. The results were compared to the proposed low-velocity inhalability criterion as well as published data on the IOM sampler. Filter weight stability and time-to-equilibrium were evaluated as these factors affect the practicality of a design. Preliminary testing of the new sampler showed good agreement with both the IOM and the proposed low-velocity inhalability curve. The capsule and filter assemblies reached equilibrium within 25h of manufacturing when conditioned at elevated temperatures. After reaching equilibrium, the capsule-filter assemblies were stable within 0.01mg.