Physical properties of the bacterial outer membrane.
Physical properties of the bacterial outer membrane.
复制标题
DOI:
10.1038/s41579-021-00638-0
复制
发表时间:
2022-04
期刊:
影响因子:
--
通讯作者:
Huang KC
中科院分区:
文献类型:
--
作者:
Sun J;Rutherford ST;Silhavy TJ;Huang KC
The ability of the Gram-negative outer membrane (OM) to act as a permeability barrier has long been appreciated, but recent studies have uncovered a more expansive and versatile role for the OM in cellular physiology and viability. Due to recent developments in microfluidics and microscopy, the structural, rheological, and mechanical properties of the OM are becoming apparent across multiple scales. In this review, we discuss recent experimental and computational studies that have revealed key molecular factors and interactions that give rise to the spatial organization, limited diffusivity, and stress-bearing capacity of the OM. These physical properties suggest broad connections between cellular structure and physiology, and we explore future prospects for further elucidation of the implications of OM construction on cellular fitness and survival.
登录
查看更多内容
影响因子:
3.4
作者:
Cayley, DS;Guttman, HJ;Record, MT Jr
通讯作者:
Record, MT Jr
影响因子:
7.7
作者:
Alvira S;Watkins DW;Troman L;Allen WJ;Lorriman JS;Degliesposti G;Cohen EJ;Beeby M;Daum B;Gold VA;Skehel JM;Collinson I
通讯作者:
Collinson I
影响因子:
64.5
作者:
BOYD, A;HOLLAND, IB
通讯作者:
HOLLAND, IB
影响因子:
13.3
作者:
Chen, Peipei;Xu, Luping;Lindner, Ariel B.
通讯作者:
Lindner, Ariel B.
DOI:
10.1073/pnas.1317497111
发表时间:
2014-04-22
影响因子:
11.1
作者:
Amir, Ariel;Babaeipour, Farinaz;Jun, Suckjoon
通讯作者:
Jun, Suckjoon