Formation of CaCO3 fibres directed by polypeptide vesicles.
Formation of CaCO3 fibres directed by polypeptide vesicles.
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DOI：
10.1039/c6tb00759g
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发表时间：
2016-05
期刊：
影响因子：
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通讯作者：
Yingqing Lu;Chunhua Cai;Jiaping Lin;Q. Zhuang
中科院分区：
文献类型：
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作者：
Yingqing Lu;Chunhua Cai;Jiaping Lin;Q. Zhuang
研究了聚谷氨酸-聚环氧丙烷-聚谷氨酸-聚丙交酯（PLGA-b-PPO-b-PLGA）三嵌段共聚物自组装多肽囊泡对碳酸钙矿化的影响。在PLGA-b-PPO-b-PLGA囊泡的介导下，获得了CaCO3纤维团簇。矿化温度、共聚物组成、共聚物浓度和Ca~（2+）浓度可调节纤维的结构。纤维生长过程的调查建议通过瞬态非晶前体的溶液-前体-固体机制。由于多肽囊泡可以作为修饰剂和模板形成无定形前体，无定形前体的性质受到囊泡结构的影响。纤维结构的变化归因于非晶颗粒的不同聚集和转变行为。这些发现可以为设计具有纤维结构的新型无机材料提供有用的信息，并丰富我们现有的知识从非晶相的结晶过程。
Mineralization behaviour of CaCO3 in the presence of polypeptide vesicles self-assembled from poly(l-glutamic acid)-block-poly(propylene oxide)-block-poly(l-glutamic acid) (PLGA-b-PPO-b-PLGA) triblock copolymers was studied. Under the mediation of PLGA-b-PPO-b-PLGA vesicles, CaCO3 fibre clusters were obtained. The structure of fibres could be regulated by the mineralization temperature, copolymer composition, copolymer concentration, and Ca2+ concentration. The investigation of the fibre growth process suggested a solution-precursor-solid mechanism via transient amorphous precursors. Since the polypeptide vesicles could serve as both the modifier and template for the formation of amorphous precursors, the properties of amorphous precursors were affected by the vesicular structure. The variation in the fibre structure was ascribed to the different aggregation and transformation behaviours of amorphous particles. These findings can provide useful information for the design of novel inorganic materials with fibrous structures and enrich our existing knowledge of the crystallization process from the amorphous phase.